Methyl 2-Acetylamino-3-Chloropropionate CAS 18635-38-6 Ramipril Intermediate Mama ≥99.0% (HPLC)
Ruifu Chemical o le taʻutaʻua taʻutaʻua o Methyl 2-Acetylamino-3-Chloropropionate (CAS: 18635-38-6) faʻatasi ai ma tulaga maualuga, vaeluaga ole Ramipril (CAS 87333-19-5).Ruifu Chemical e mafai ona tuʻuina atu i le lalolagi atoa, tau faʻatauvaʻa, auaunaga sili ona lelei, laʻititi ma tele tele o loʻo avanoa.Fa'atau Methyl 2-Acetylamino-3-Chloropropionate,Please contact: alvin@ruifuchem.com
Igoa Vailaau | Methyl 2-Acetylamino-3-Chloropropionate |
Synonyms | LN-Acetyl-β-Chloroalanine Methyl Ester;Methyl (R)-2-Acetamido-3-Chloropropanoate;N-Acetylmine-3-Chloro-L-Alaninemethyl Ester;Methyl N-Acetyl-3-Chloro-L-Alaninate;Methyl N-Acetyl-3-Chloroalaninate;Ac-DL-Ala(Cl)-OMe |
Tulaga Fa'asoa | I Fa'atauga, Gaosiga Fa'apisinisi |
Numera CAS | 18635-38-6 |
Fuafua mole | C6H10ClNO3 |
Molecular Weight | 179.60 g/mol |
Lisi Lisi | 102.0~105.0 ℃ |
COA & MSDS | Avanoa |
Amataga | Shanghai, Saina |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga | I'uga |
Fa'aaliga | Pa'epa'e i le Pa'epa'e Pa'epa'e | E usitaia |
Lisi Lisi | 102.0~105.0 ℃ | 102.0~105.0 ℃ |
Ma'imau ile Fa'amago | ≤0.50% | 0.26% |
Ta'amilosaga Fa'apitoa | -13.0° i le -16.0° | -13.15° |
Mama / Suʻesuʻega Metotia | ≥99.0% (HPLC) | 99.27% |
Alaleo Infrared | O gatasi ma le Fauga | E usitaia |
1H NMR Alaleo | O gatasi ma le Fauga | E usitaia |
Fa'ai'uga | Ua uma ona fa'ata'ita'iina le oloa ma fa'amalieina fa'atonuga |
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Methyl 2-Acetylamino-3-Chloropropionate (CAS: 18635-38-6), vaeluaga ole Ramipril (CAS 87333-19-5).O le Ramiprilat o le metabolite malosi o le ramipril ma e galue o se angiotensin-converting enzyme inhibitor (pKi = 9.08 i le loto o le tagata) e taofia ai le liua o le angiotensin I i le angiotensin II ma le faʻaleagaina o le bradykinin, ma puipuia ai le vasoconstriction.E le gata i lea, o le ramiprilat o loʻo lipotia mai e faʻalavelave i le tulimataʻiina o le B2 kinin receptors i le endothelial cell membranes e puipuia atili ai le bradykinin signaling.I le faaopoopo atu i ona aafiaga cardioprotective i faʻataʻitaʻiga manu ma suʻesuʻega falemaʻi, ua lipotia mai e le ramiprilat e taofia ai le matrix metalloproteinase-3 ma le -9 gaioiga i faʻamaʻi faʻamaʻi o Crohn.