Lapatinib Intermediate CAS 231278-84-5 Mama>98.0% (HPLC)
Igoa Vailaau | 5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde |
Synonyms | Lapatinib Intermediate 3;5-[4-[[3-Chloro-4-[(3-Fluorophenyl)methoxy]phenyl]amino]-6-Quinazolinyl]-2-Furancarboxaldehyde;5-[4-((3-Chloro-4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-Furaldehyde |
Numera CAS | 231278-84-5 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C26H17ClFN3O3 |
Molecular Weight | 473.90 |
Lisi Lisi | 225.0 i le 235.0 ℃ |
Malosi | 1.407±0.06 g/cm3 |
Fa'asino Upu | 1.694 |
COA & MSDS | Avanoa |
Amataga | Shanghai, Saina |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Samasama lanu samasama i le samasama pauta malo |
Mama / Suʻesuʻega Metotia | >98.0% (HPLC) |
Lisi Lisi | 225.0~235.0 ℃ |
Ma'imau ile Fa'amago | <1.00% |
Toega i luga o le mumu | <0.50% |
Aofa'i Fa'aleaga | <2.00% |
Metala mamafa (pei o le Pb) | <20ppm |
Tulaga Su'ega | Enterprise Standard |
Fa'aoga | Tulaga o API (CAS 388082-77-7) |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde (CAS: 231278-84-5) ose mea vavalo ole API (CAS 388082-77-7) ).(CAS 388082-77-7) o se vailaʻau faʻatatau i le kanesa o le susu na atiaʻe e British GlaxoSmithKline Co. O le tyrosine kinase inhibitor lea e mafai ona faʻamalosia lelei le gaioiga tyrosine kinase o tagata epidermal growth factor receptors 1 ma 2 (ErbB1, ErbB2).E mafai ona fa'apitoa ona galue i ni auala 'ese'ese, fa'amautinoa e le mafai e sela o le kanesa o le susu ona maua fa'ailoga o le tuputupu a'e.E taofia ai le intracellular EGFR (ErbB-1) ma le HER2 (ErbB-2) ATP nofoaga, puipuia le tumo cell phosphorylation ma le faʻagaoioia, poloka faʻamaufaʻailoga lalo-tulafono e ala i le homogeneity ma heterogeneity o EGFR (ErbB-1) ma HER2 (ErbB-1) dimerization.