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Ibrutinib Intermediate CAS 330792-70-6 Mama>98.0% (HPLC) Ata Fa'aalia
  • Ibrutinib Intermediate CAS 330792-70-6 Mama>98.0% (HPLC)

Ibrutinib Intermediate CAS 330792-70-6 Mama>98.0% (HPLC)

Fa'amatalaga Puupuu:

5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile

CAS: 330792-70-6

Mama: >98.0% (HPLC)

Fa'aaliga: Pa'epa'e-Pa'epa'e i le Pa'u Samasama Malamalama

Intermediate of Ibrutinib (CAS: 936563-96-1) 

Fa'afeso'ota'i: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Fa'amatalaga Oloa

Oloa Fa'atatau

Faailoga o oloa

Intermediates o Ibrutinib:

Ibrutinib CAS 936563-96-1
3-Hydroxypiperidine CAS 6859-99-0
1-Boc-3-Hydroxypiperidine CAS 85275-45-2
(S)-1-Boc-3-Hydroxypiperidine CAS 143900-44-1
4-Phenoxybenzoic Acid CAS 2215-77-2
4-Phenoxyphenylboronic Acid CAS 51067-38-0
4-Aminopyrazolo [3,4-d]pyrimidine CAS 2380-63-4
4-Amino-3-Iodo-1H-Pyrazolo[3,4-d]pyrimidine CAS 151266-23-8
Ibrutinib Deacrylloylpiperidine CAS 330786-24-8
5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile CAS 330792-70-6

Meatotino tau vailaau:

Igoa Vailaau 5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
Synonyms Ibrutinib Intermediate N-3;3-Amino-5-(4-Phenoxyphenyl)pyrazole-4-Carbonitrile;3-Amino-4-Cyano-5-(4-Phenoxyphenyl)pyrazole;5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
Numera CAS 330792-70-6
Tulaga Fa'asoa I Fa'atauga, Oloa Fua e O'o i Tone
Fuafua mole C16H12N4O
Molecular Weight 276.29
Malosi 1.37±0.10g/cm3
COA & MSDS Avanoa
Amataga Shanghai, Saina
Fa'ailoga Ruifu Chemical

Fa'amatalaga:

Aitema Fa'amatalaga
Fa'aaliga Pa'epa'e-Pa'epa'e i le Pa'u Samasama Malamalama
Mama / Suʻesuʻega Metotia >98.0% (HPLC)
Ma'imau ile Fa'amago <1.00%
Toega i luga o le mumu <0.50%
Aofa'i Fa'aleaga <2.00%
Metala mamafa (pei o le Pb) <20ppm
1 H NMR Alaleo O gatasi ma le Fauga
Tulaga Su'ega Enterprise Standard
Fa'aoga Intermediate of Ibrutinib (CAS: 936563-96-1)

Paket & Teuina:

afifi: Fagu, taga pepa alumini, 25kg / Cardboard Drum, pe tusa ai ma manaoga o tagata faatau.

Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu.

Tulaga lelei:

1

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330792-70-6 - Talosaga:

5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile (CAS: 330792-70-6) o se vaeluaga ole Ibrutinib (CAS: 936563-96-1).Ibrutinib o loʻo faʻaalia ai le malosi ma le le mafai ona faʻaaogaina le faʻalavelave faʻalavelave ma le filifilia mo le Btk enzymatic activity.I le BCR ala-faagaoioia DOHH2 laina cell, Ibrutinib taofia autophosphorylation o Btk, phosphorylation o Btk's physiological substrate PLCγ, ma le phosphorylation o le isi pito i lalo kinase, ERK ma IC50 o 11 nM, 29 nM ma 13 nM, faasologa.O le Ibrutinib o loʻo faʻaalia ai le faʻaogaina o le faʻaogaina o le cytotoxicity i totonu ole lymphocytic leukemia (CLL).E le gata i lea, o le Ibrutinib e faʻaosofia ai le oti o le cell e faʻatatau i le faʻagaioiina o le ala caspase ma faʻafefe ai le gafatia o sela CLL e faʻateleina pe a uma le faʻailoga TLR.

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