Lapatinib Ditosylate Monohydrate CAS 388082-78-8 Mama>99.0% (HPLC)
Igoa Vailaau | Lapatinib Ditosylate Monohydrate |
Synonyms | N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine |
Numera CAS | 388082-78-8 |
Tulaga Fa'asoa | E tele |
Fuafua mole | C29H26ClFN4O4S·2(C7H8O3S)·H2O |
Molecular Weight | 943.48 |
COA & MSDS | Avanoa |
Amataga | Shanghai, Saina |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Samasama lanu samasama i le pauta tioata samasama |
Mama / Suʻesuʻega Metotia | ≥99.0% (HPLC) |
Lisi Lisi | 240.0~242.0 ℃ |
Susū (KF) | 1.9~2.4% |
Le mama nofofua | ≤0.50% |
Aofa'i Fa'aleaga | ≤1.00% |
Metala mamafa (pei o le Pb) | ≤20ppm |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | API;Mo togafitiga o gasegase e maua i le kanesa o le susu |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8) o le masima ditosylate oCAS 231277-92-2, o se quinazoline fa'aigoaina, fa'aogaina tautala ma fa'alavelave fa'alavelave.E toe faʻafoʻisia poloka phosphorylation o le epidermal growth factor receptor (EGFR), ErbB2, ma le Erk-1 ma-2 ma AKT kinases;e taofia ai foi le maualuga o le porotini D cyclin D i laina sela tumo tagata ma xenografts.EGFR ma ErbB2 ua aʻafia i le tuputupu aʻe o ituaiga tumo eseese.Na fa'alauiloaina mo le togafitia o le kanesa o le susu maualuga po'o le metastatic HER2 (ErbB2) i fafine na maua muamua togafitiga.O le vailaʻau na maua ma atiaʻe e GlaxoSmithKline.