5-Amino-3-(Trifluoromethyl)picolinonitrile CAS 573762-62-6 Apalutamide Amioga Mamā >98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua o le 5-Amino-3-(Trifluoromethyl) picolinonitrile (CAS: 573762-62-6) faʻatasi ai ma le maualuga, vaeluaga o Apalutamide (CAS: 956104-40-8).Ruifu Chemical e mafai ona tuʻuina atu i le lalolagi atoa, tau faʻatauvaʻa, auaunaga sili ona lelei, laʻititi ma tele tele o loʻo avanoa.Fa'atau Apalutamide Intermediates,Please contact: alvin@ruifuchem.com
| Igoa Vailaau | 5-Amino-3-(Trifluoromethyl)picolinonitrile |
| Synonyms | 5-Amino-3-(Trifluoromethyl)pyridine-2-Carbonitrile;5-Amino-3-(Trifluoromethyl)2-Cyanopyridine;5-Amino-2-Cyano-3-(Trifluoromethyl)pyridine;Apalutamide le mama 10 |
| Tulaga Fa'asoa | I Fa'atauga, Gaosiga Fa'apisinisi |
| Numera CAS | 573762-62-6 |
| Fuafua mole | C7H4F3N3 |
| Molecular Weight | 187.12 g/mol |
| Malosi | 1.45±0.10g/cm3 |
| COA & MSDS | Avanoa |
| Amataga | Shanghai, Saina |
| Vasega o Tulaga Lamatia | 6.1 |
| Fa'aputuga Vaega | Ⅲ |
| Vaega | Intermediate o Apalutamide (CAS: 956104-40-8) |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Tulaga Fa'atonu | I'uga |
| Fa'aaliga | Samasama Malamalama i Samasama Solid | E usitaia |
| Vai saunia e Karl Fischer | <0.50% | 0.35% |
| Mama / Suʻesuʻega Metotia | >98.0% (HPLC) | 99.03% |
| Alaleo Infrared | O gatasi ma le Fauga | E usitaia |
| 1H NMR Alaleo | O gatasi ma le Fauga | E usitaia |
| Fa'ai'uga | Ua uma ona fa'ata'ita'iina le oloa ma fa'amalieina fa'atonuga | |
| Fa'atatauga | Intermediate o Apalutamide (CAS: 956104-40-8) | |
afifi:Fa'ato'aga Fa'alili, Ato pepa alumini, 25kg/Cardboard Drum, pe tusa ai ma mana'oga o tagata fa'atau.
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Fa'afefea ona Fa'atau?Fa'amolemole fa'afeso'ota'iDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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5-Amino-3-(Trifluoromethyl)picolinonitrile (CAS: 573762-62-6), o se pyridine heterocyclic organic compound, lea e mafai ona faʻaaogaina e avea ma vailaʻau faʻapitoa.5-Amino-3-(Trifluoromethyl)picolinonitrile ose vaeluaga ole Apalutamide (CAS: 956104-40-8).Apalutamide o se antiandrogen lona lua o loʻo faʻaaogaina i togafitiga o le kanesa prostate.O se faʻalavelave malosi o le androgen receptor ma le IC50 tau o le 16 nM.Faʻasalaina androgen receptors, ma faʻafefe ai le faʻaliliuga faaniukilia, faʻamauina DNA ma le faʻagaioiina o tusitusiga.O le Apalutamide o lo'o i ai togafitiga fa'afoma'i i le kanesa prostate e le-metastatic, castration-resistant.
O le Apalutamide e fa'aaogaina e togafitia ai nisi o ituaiga o kanesa prostate e tete'e castration po'o le kanesa prostate e le'i sosolo i isi vaega o le tino, ae e le'i fesoasoani i isi togafitiga faafoma'i.Apalutamide o loʻo i totonu o le vasega o vailaʻau e taʻua o le inhibitors receptor androgen.E galue e ala i le polokaina o aafiaga o le androgen e taofi ai le tuputupu aʻe ma le sosolo o sela o le kanesa.I le aso 17 o Setema, 2019, na faʻamaonia ai e le Food and Drug Administration le Apalutamide (ERLEADA, Janssen Biotech, Inc) mo tagata mamaʻi e maua i le metastatic castration-sensitive prostate cancer (mCSPC).Apalutamide na muamua faʻamaonia i le 2018 mo tagata mamaʻi e leai ni metastatic castration-resistant prostate cancer.
