Trelagliptin Succinate Intermediate CAS 865759-24-6 Mama>98.0% (HPLC)

Fa'amatalaga Puupuu:

Trelagliptin Succinate Intermediate-int D

CAS: 865759-24-6

Mama: >98.0% (HPLC)

Fa'aaliga: Pa'epa'e-Pa'epa'e i Maila Samasama Malamalama

Intermediate of Trelagliptin Succinate (CAS: 1029877-94-8) mo togafitiga o le maʻisuka ituaiga 2

Fa'afeso'ota'i: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Fa'amatalaga Oloa

Oloa Fa'atatau

Faailoga o oloa

Fa'amatalaga:

Fa'atauga Fa'atauga Trelagliptin Succinate Feso'ota'i Fesoota'iga:
6-Chloro-3-Methyluracil CAS 4318-56-3
2-Cyano-5-Flurobenzyl Bromide CAS 421552-12-7
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
Trelagliptin Succinate Intermediate-int D CAS 865759-24-6
Trelagliptin Succinate CAS 1029877-94-8
Please contact: alvin@ruifuchem.com

Meatotino tau vailaau:

Igoa Vailaau	Trelagliptin Succinate Intermediate-int D
Synonyms	2-((6-Chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile;2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-4-fluorobenzonitrile
le mama	Trelagliptin Le mama 17
Tulaga Fa'asoa	I Fa'atauga, Fua Fa'atau
Numera CAS	865759-24-6
Fuafua mole	C13H9ClFN3O2
Molecular Weight	293.68 g/mol
Malosi	1.49±0.10g/cm3
Temp.	Nofoaga malulu & mago
COA & MSDS	Avanoa
Fa'ailoga	Ruifu Chemical

Fa'amatalaga:

Aitema	Tulaga Fa'atonu	I'uga
Fa'aaliga	Pa'epa'e-Pa'epa'e i le tioata Samasama Malamalama	Fa'atatau
Fa'ailoaga
HPLC	Ole taimi ole fa'atumauina ole fa'ata'ita'iga ole pito maualuga tele ole fa'ata'ita'iga e fa'atatau ile tulaga fa'asino	Fa'atatau
IR - Alaleo Infrared	IR absorption spectrum o fa'ata'ita'iga ma fa'ata'ita'iga e fetaui lelei	Fa'atatau
Asiasiga
Ma'imau ile Fa'amago	<0.50%	0.3%
Aofa'i Fa'aleaga	<2.00%	Fa'atatau
Mama / Suʻesuʻega Metotia	>98.0% (HPLC)	99.1%
Fa'ai'uga	Ua fa'ata'ita'iina le oloa ma fa'amalieina fa'amatalaga

Paket/Teuga/Va'a:

afifi:Fagu, Ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau.
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Au'aunaga Fa'aaufa'atasi: E amata mai i le kalama i le kilokalama

Tulaga Maualuga: Faʻavae se faiga faʻamautinoaga lelei atoatoa

FAQ:

Fa'afefea ona Fa'atau?Fa'amolemole fa'afeso'ota'iDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Tausaga Aafiaga?E sili atu nai lo le 15 tausaga o le poto masani i le gaosiga ma le auina atu i fafo o le tele o tulaga maualuga o vailaʻau faʻapitoa poʻo vailaʻau lelei.

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Pepa?A maeʻa le faʻatau atu auaunaga: COA, MOA, ROS, MSDS, ma isi mea e mafai ona tuʻuina atu.

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Talosaga:

2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile (CAS: 865759-24-6) o loʻo faʻaaogaina e avea o se vaeluaga ole Trelagliptin Succinate (CAS: 1029877-94-8).Trelagliptin Succinate, atiaʻe e Takeda, Iapani, faʻalauiloa ia Mati 2015, i lalo o le igoa tau fefaʻatauaʻiga Zafatek, e faʻaaogaina e togafitia ai le maʻisuka ituaiga 2.O le Trelagliptin ose dipeptidyl peptidase IV(DPP-4) fa'ato'aga e sili ona umi e galue e ala i le filifili ma fa'aauau le taofia o le DPP-4 e pulea ai le maualuga o le suka toto.Trelagliptin o le vailaʻau muamua o le hypoglycemic i vaiaso taʻitasi i luga o le maketi, ma e manaʻomia ona ave faʻatasi i le aso faʻatasi DPP-4 inhibitors i luga o le maketi.Ole aoga ole vaila'au a Zafatek e mautinoa lava e maua ai togafitiga sili atu ona faigofie mo tagata ma'i suka.O loʻo faʻamoemoe e faʻaleleia atili le faʻaogaina ma le tausisia o gasegase.ia Mati 26, 2015, Iapani pharmaceutical sauai Takeda faailoa mai o le fualaau fou o le maʻisuka Zafatek na faʻamaonia e le Matagaluega o le Soifua Maloloina, Leipa ma le Uelefea (MHLW) a Iapani mo togafitiga o le maʻisuka ituaiga 2.O le faʻatagaga ua faʻailogaina ai Zafatek o le avea muamua ma vailaʻau hypoglycemic oral i vaiaso taʻitasi i luga o le maketi i le lalolagi, ma o loʻo faʻatusalia ai foi se poloka poloka na paʻu e Takeda i le maketi o le maʻisuka.
Trelagliptin ose dipeptidyl peptidase IV (DPP-4) inhibitor e ta'i vaiaso e pulea ai le maualuga o le suka i le toto e ala i le filifili ma fa'aauau ona taofiofia le DPP-4.O le DPP-4 o se enzyme e mafai ona amataina le le faʻaaogaina o le incretin (glucagon-like peptide -1 (GLP-1) ma le glucose-dependent insulinotropic polypeptide (GIP)), lea e iai sona sao taua i le faatonutonuina o le kulukose toto.O le taofiofia o le DPP-4 e mafai ona fa'atuputeleina ai le fa'aogaina o le inisalini e fa'alagolago i le maualuga o le suka toto, ma pulea ai le maualuga o le suka toto.O le tuʻuina atu o le Trelagliptin NDA e faʻavae i luga o faʻamatalaga aoga ma le saogalemu mai le tele o vaega III faʻataʻitaʻiga faʻataʻitaʻiga na faia i tagata Iapani e maua i le maʻisuka ituaiga 2.O le aoga o Trelagliptin ua faʻamaonia i faʻataʻitaʻiga uma, ma o loʻo i ai le saogalemu lelei ma le gafatia.Trelagliptin Administration fa'atasi i le vaiaso e mafai ona pulea lelei le maualuga o le suka toto ma e fa'amoemoe e fa'aleleia atili ai le tausisia o vaila'au.