4-Chloro-6-Iodoquinazoline CAS 98556-31-1 Mama>98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua o le 4-Chloro-6-Iodoquinazoline (CAS: 98556-31-1) ma le maualuga.Ruifu Chemical e mafai ona tuʻuina atu i le lalolagi atoa, tau faʻatauvaʻa, auaunaga sili ona lelei, laʻititi ma tele tele o loʻo avanoa.Fa'atau 4-Chloro-6-Iodoquinazoline,Please contact: alvin@ruifuchem.com
Igoa Vailaau | 4-Chloro-6-Iodoquinazoline |
Synonyms | 6-Iodo-4-Chloroquinazoline |
Tulaga Fa'asoa | I Fa'atauga, Gaosiga Fa'apisinisi |
Numera CAS | 98556-31-1 |
Fuafua mole | C8H4ClIN2 |
Molecular Weight | 290.49 g/mol |
Lisi Lisi | 175.0 i le 179.0 ℃ |
Malosi | 2.017±0.06 g/cm3 |
Fa'asinoga Fa'asinomaga n20/D | 1.739 |
Ma'ale'ale | Ea maaleale |
COA & MSDS | Avanoa |
Amataga | Shanghai, Saina |
Fa'ailoga | Ruifu Chemical |
Aitema | Tulaga Fa'atonu | I'uga |
Fa'aaliga | Eleele Samasama e Samasama-Enaena Pata | Eleele Samasama Pata |
Lisi Lisi | 175.0 i le 179.0 ℃ | 177.2 ℃ |
Ma'imau ile Fa'amago | <1.00% | 0.15% |
Mama / Suʻesuʻega Metotia | >98.0% (HPLC) | 98.43% |
1H NMR Alaleo | O gatasi ma le Fauga | E usitaia |
Fa'ai'uga | Ua uma ona fa'ata'ita'iina le oloa ma fa'amalieina fa'atonuga | |
Fa'atatauga | Intermediate o Lapatinib / Lapatinib Ditosylate Monohydrate |
afifi:Fa'ato'aga Fa'alili, Ato pepa alumini, 25kg/Cardboard Drum, pe tusa ai ma mana'oga o tagata fa'atau.
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Fa'afefea ona Fa'atau?Fa'amolemole fa'afeso'ota'iDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Maketi Autu?Faʻatau atu i maketi i totonu o le atunuʻu, Amerika i Matu, Europa, Initia, Korea, Iapani, Ausetalia, ma isi.
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Tulaga leleiFaamautinoaga?Fa'atonuga lelei faiga.O meafaigaluega faʻapitoa mo suʻesuʻega e aofia ai le NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
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MOQ?Leai MOQ.Laititi oka e talia.
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4-Chloro-6-Iodoquinazoline (CAS: 98556-31-1) o se vaeluagalemu i le tuufaatasiga o Lapatinib (CAS: 231277-92-2) / Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8).
O le Lapatinib o se vailaʻau fou e faʻatatau i le kanesa o le susu na atiaʻe ma gaosia e GlaxoSmithKline, lea na faʻamaonia e le US Food and Drug Administration ia Mati 13, 2007. O le faʻamaoniga o loʻo faʻamaonia nei o loʻo tuʻufaʻatasia ma le capecitabine mo le kanesa o le susu maualuga poʻo metastatic, ma gasegase o le susu. e tatau ona togafitia i isi vailaʻau faʻasolosolo muamua.O lona igoa tau fefa'ataua'iga i le Iunaite Setete o Tykerb.O Tesema 14, 2007, na faʻamaonia ai e le European Medicines Agency (EMEA) le lisi o Lapatinib i Europa i lalo o le igoa tau fefaʻatauaʻiga Tyverb.O togafitiga fa'atatau mole mole mo le kanesa o le susu e faasino ile togafitiga ole oncogenes ma fa'amatalaga fa'atusa e feso'ota'i ma le tupu ma le atina'eina ole kanesa o le susu.O vaila'au fa'atatau mole mole e taofia pe tape ai sela tumo e ala i le polokaina o le fa'aliliuina o fa'ailo i sela tumo po'o sela fa'afeso'ota'i e pulea ai suiga i le fa'aaliga o ga'o.O le Lapatinib o se molelaʻau laiti epidermal growth factor tyrosine kinase inhibitor.O fa'ata'ita'iga fa'afoma'i ua fa'aalia ai mo tagata mama'i o le kanesa o le susu o le HER2 ua atia'e le tete'e atu i le Roche's Herceptin (Herceptin), Lapatinib e lelei lona a'afiaga.Su'ega in vitro, Lapatinib sa i ai se aafiaga taua fa'alavelave fa'atupu i luga o Her-2 overexpressing laina sela o le kanesa o le susu.I le Vaega I faʻataʻitaʻiga o le kanesa o le susu maualuga ma Her-2 overexpression, Lapatinib foi e maualuga lona aoga ma e leai se faʻafeagai ma Herceptin (trastuzumab).Ona o lona fausaga o se mole laʻititi, e le pei o Herceptin (trastuzumab), e mafai ona ulu i totonu o le pa puipui o le toto-faiʻai ma e iai sona aafiaga faʻapitoa i le faiʻai metastasis o le kanesa o le susu.