Caspofungin Acetate Cancidas CAS 179463-17-3 falegaosimea API Mama maualuga
Faumea e maualuga le mama ma mautu lelei
Igoa vaila'au: Caspofungin Acetate
CAS: 179463-17-3
API Tulaga Maualuga, Gaosiga Fa'apisinisi
Igoa Vailaau | Caspofungin Acetate |
Synonyms | Cancidas;MK-0991 Acetate;L-743872 Acetate |
Numera CAS | 179463-17-3 |
CAT Numera | RF-API58 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i le selau Kilograms |
Fuafua mole | C52H88N10O15·2C2H4O2 |
Molecular Weight | 1213.42 |
Lisi Lisi | >197℃ |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e po'o Toeitiiti Pa'epa'e Pa'epa'e |
Faailoaina IR | IR: Alaleo ole Su'ega fa'ata'ita'iga e tatau ona fa'aa'ai ma le Caspofungin Acetate Reference Standard |
Fa'ailoga HPLC | HPLC: O le taimi fa'atumauina o le maualuga maualuga e maua mai le su'ega fofo e tatau ona ogatusa ma le mea na maua mai le vaifofo masani, e pei o le su'ega ile Assay |
Malamalama ma Lanu | O le fofo e tatau ona manino ma leai ni lanu |
Ta'amilosaga Fa'apitoa | -102.0° ~ -108.0° |
pH | 5.0~7.0 |
Vai | ≤10.0% |
Mea Fa'atatau I | (I luga ole Anhydrous ma le Acetic Acid Free Fa'avae) |
Le mama A | ≤0.10% |
Le mama B | ≤0.10% |
Le mama D | ≤0.30% |
Le mama E | ≤0.10% |
Le Fa'amamafaina F | ≤0.10% |
Le fa'amamafaina le mama G | ≤0.10% |
Pneumocandin B0 | ≤0.10% |
Nofofua Le iloa le mama | ≤0.10% |
Aofa'i Fa'aleaga | ≤1.0% |
Mea Fa'atatau II | ≤0.10% |
Solvents totoe | |
Ethyl Acetate | ≤5000ppm |
Ethanol | ≤5000ppm |
Methanol | ≤5000ppm |
Acetonitrile | ≤410ppm |
Tetrahydrofuran | ≤720ppm |
Acetic Acid Content | 9.0%~11.0% (Fa'atatau ile Anhydrous Fa'avae) |
Ethylendiamine | ≤0.10% |
Toega i luga o le mumu | ≤0.10% |
Metala mamafa (pei o le Pb) | ≤10ppm |
Su'ega / Su'esu'ega Metotia | 97.0%~102.0% (I luga ole Anhydrous ma Solvent Free Fa'avae) |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | Mea Fa'afoma'i Gaoioiga (API) |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
Caspofungin Acetate (CAS: 179463-17-3) o se lipopeptide antifungal vailaʻau.O le Caspofungin acetate mo le tui na faʻatagaina muamua e le FDA i Amerika, ma le EMEA i Europa, i le 2001. O le Caspofungin Acetate o se vai soluble, faʻamautu, aza-substituted semisynthetic derivative o Pneumocandin B, o se oloa faʻafefeteina o le fungus Zalerion arboricola.O le lipopeptide caspofungin, e taofia ai le tuʻufaʻatasia o le 1,3-beta-D-glucans o loʻo i ai i totonu o le puipui o le sela, lea e oʻo atu ai i le lysis faʻapitoa o sela faʻamaʻi.O le tuufaatasiga e fugicidal nai lo le fungistatic, o se mea e le masani ai i totonu o vailaau faʻamaʻi.Caspofungin sa masani ona sili atu le malosi nai lo amphotericin B, flucytosine, fluconazole ma itraconazole faasaga i ituaiga Candida.