CDI CAS 530-62-1 N,N'-Carbonyldiimidazole Feso'ota'iga Reagent Mama >98.0% (T) Falegaosimea

N,N'-Carbonyldiimidazole (CDI) (CAS: 530-62-1), peptide coupling reagent, faʻaaogaina i le tuʻufaʻatasia o peptides.O le CDI o se peptide coupling reagent, e faʻaaogaina i le tuʻufaʻatasiga o peptides.E fa'afefeteina ma le carboxylic acids e fai ai acyl imidazoles;o le tali mulimuli ane ma amine e fausia ai amide e sologa lelei.
E taua tele le condensation sui e fa'apipi'i nucleoside triphosphates, peptide-triphosphate ma triphosphate;taua ole vaeluagalemu e synthesize acylimidazole.
I le avea ai o se sui faʻamalosi mo le faʻapipiʻiina o triphosphonucleosides, peptides ma esters;Ma o se mea taua tele mo le tuʻufaʻatasia o le acyl imidazole ma le pyridoxamide, le puipuiga o vaega faʻapipiʻi meaola ma le protein peptide chain connection.
Peptide coupling reagent CDI e galue e pei o se so'o fa'apipi'i ma fa'aogaina mo le so'ofa'atasi o amino acids ina ia saunia ai le peptide i le fa'aogaina o meaola.E faʻaaogaina foi i le sauniuniga o beta-keto sulfones, sulfoxides ma beta-enamino acid derivatives.E faʻaaogaina e faʻaliliu ai ava malosi ma amine i carbamates, esters, ma ureas.O lo'o a'afia i le saunia o le imidazole e ala i le tali atu ma le formic acid.E le gata i lea, o loʻo faʻaaogaina i le tuʻufaʻatasia o mea faʻapipiʻi polyamides dipolar.I le faaopoopo atu i lenei mea, ua manatu o se mea e tutusa ma le phosgene ma faʻaaogaina e saunia ai le asymmetric bis alkyl carbonate.
O le CDI o se mea e maua mai i le imidazole, ma o lona fausaga o le imidazole o loʻo i ai se faʻamaufaʻailoga P tele, ma o loʻo i ai se paʻaga eletonika i luga o le sp2 orbital lea e le faʻapipiʻi ai le tasi o le nitrogen atom.O nei mea e iloa ai o le CDI o loʻo i ai se gaioiga malosi faʻamalosi, e mafai ona tali atu i le amonia, ava malosi, vailaʻau ma isi vaega faʻatino, ma faʻapipiʻi le tele o mea faʻapipiʻi e faigata ona maua e ala ile vailaʻau masani.E faʻaaogaina lautele e avea o se enzyme ma le protein binder, o se vaeluaga i le tuʻufaʻatasiga o vailaʻau faʻamaʻi, aemaise lava o se soʻo faʻapipiʻi mo faʻapipiʻi polypeptide.
O le CDI o se fa'a'ese'ese feso'ota'iga e leai se umi e fa'aogaina e fa'aluaina ai amine muamua i vaega fa'atino o le karboxyllic acid.O le CDI e tali atu i le carboxylate ion (COO-) o polotini poʻo isi mea faʻalaʻau, faʻatupuina se mea faʻalavelave faʻafefeteina e mulimuli ane faʻaalia ma se vaega amino (-NH2).E mafai ona fa'aoga lenei mea fa'afefete e fa'alua ai polotini se lua, ma e masani ona fa'aogaina i le polotini le fa'aogaina i se lagolago mautu po'o se membrane.Fa'afaigofie, e mafai ona fa'aogaina le CDI i le vai ma le organic solvent systems.
Fa'aaogaina e fai ma vaila'au ma vaila'au.