Cisatracurium Besylate CAS 96946-42-8 Suʻega 95.0% ~ 102.0% API Faleoloa Maualuga Maualuga
Faumea e maualuga le mama ma mautu lelei
Igoa vaila'au: Cisatracurium Besylate
CAS: 96946-42-8
API Tulaga Maualuga, Gaosiga Fa'apisinisi
Igoa Vailaau | Cisatracurium Besylate |
Numera CAS | 96946-42-8 |
CAT Numera | RF-API13 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C53H72N2O12.2C6H5O3S |
Molecular Weight | 1243.49 |
Lisi Lisi | 90.0~93.0 ℃ |
Tulaga Va'a | I lalo ole Temperature Ambient |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Paʻepaʻe poʻo Toeitiiti Paʻepaʻe Paʻu, E leai se manogi, Laititi Hygroscopic |
Solubility | Solu saoloto i le dichloromethane, acetonitrile, solute laititi i le vai |
Ta'amilosaga Fa'apitoa | -35.0° i le -45.0° (C=10mg/ml, 0.1mg/ml benzene sulfonic acid) |
Fa'ailoaga | Fa'amuta fa'atasi ma vai fa'afefete hydrochoric acid, fa'ato'a fa'atete'e bismuth potassium iodide TS, o le a maua mai timuga samasama. |
Fa'ailoaga | 1. HPLC ;2. IR |
Su'ega | 95.0~102.0% (C65H82N2O18S2 ile fa'amamago) |
pH | 3.5 i le 5.0 |
Malamalama & Lanu o le Fofo | E tatau ona manino ma le lanu |
Ma'imau ile Fa'amago | ≤2.0% |
Toega i luga o le mumu | ≤0.20% |
Metala mamafa | ≤20ppm |
Trans-Trans Isomer | ≤0.50% |
Cis-Trans Isomer | ≤0.50% |
Mono-quaternaries | ≤1.50% |
So'o seisi lava le mama | ≤1.50% |
Aofa'i Fa'aleaga | ≤5.0% |
Optical Isomer SS-Isomer | ≤1.50% |
Optical Isomer RS- Isomer | ≤1.00% |
Sulfate | ≤50ppm |
Ethyl | ≤0.50% |
Acetone | ≤0.50% |
Methanol | ≤0.3% |
Dichloromethane | ≤0.06% |
Acetonitrile | ≤0.041% |
Methylbenzene | ≤0.089% |
Solvents totoe Acetonitrile | ≤410ppm |
Tulaga Su'ega | Pharmacopoeia Saina (CP) |
Fa'aoga | Mea Fa'afoma'i Gaoioiga (API) |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
Cisatracurium Besylate (CAS 96946-42-8) o le masima benzene sulfonate o le atracurium.O se ituaiga o fa'agaioia fa'akomepiuta non-depolarizing maso relaxants ma lona matafaioi tutusa e pei o tubocurarine.Ole fua ole togafitiga e le afaina ai le fatu, ate ma fatuga'o.E leai foi se meatotino faaputuputu.E mafai fo'i ona fa'aosoina le fa'asa'olotoina o le histamine pe a fa'aaoga i tui tetele.Mo le malolo maso po'o le manava e mana'omia ile taotoga, pe a fa'atusatusa i le falema'i o lo'o iai nei vaila'au fa'ama'i fa'amama-mamago, cisatracurium besylate e le fa'afefeteina e ala ile ate po'o fatuga'o, ma e mautu le cardiovascular;o lona aafiaga o musele malolo e 3 taimi sili atu le malosi e pei o le atracurium e aunoa ma ni aafiaga cardiovascular itu.Cisatracurium besylate e masani ona faʻaaogaina i faʻamaʻi lautele, ma e mafai ona faʻaaogaina lautele i le intubation, togafitia o le ate ma fatugaʻo faʻaleagaina, faʻaaogaina i taotoga cardiovascular ma tagata matutua ma tamaiti.Fa'atusatusa i le atracurium, o lenei oloa e leai ni a'afiaga leaga fa'alagolago i fua ole histamine fa'amalolo;ae ui i lea, o le tulaga le lelei o tagata mama'i e faaletonu le ate ma fatuga'o e tatau ona fa'atonuina ma le fa'aeteete.Talu mai le 1996 mo le taimi muamua na ulufale ai lenei vailaʻau i le maketi i Peretania, ua faasolosolo malie ona faʻaaogaina e atunuu i fafo e sui ai le vecuronium ma le atracurium e avea ma faʻauluuluga o maso faʻamaʻi.