Cyano-Irbesartan CAS 138401-24-8 Mama >98.0% (HPLC) Irbesartan Intermediate Factory
Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1
Igoa Vailaau | Cyano-Irbesartan |
Synonyms | CyanoIrbesartan;Irbesartan Cyano Le mama;Irbesartan Hydrocarbon;Irbesartan le mama 6;2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]e le-1-en-4-one;4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4,4]non-1-en-3-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile |
Numera CAS | 138401-24-8 |
CAT Numera | RF-PI1892 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C25H27N3O |
Molecular Weight | 385.51 |
Malosi | 1.15 |
Solubility (Soluble in) | Methanol |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e ile Toeitiiti Pa'epa'e Pa'epa'e ile Crystal |
Mama / Suʻesuʻega Metotia | >98.0% (HPLC) |
Mama | >97.0% (Fa'atasi ma le Nitrogen Aofa'i) |
Lisi Lisi | 91.0 i le 95.0 ℃ |
Ma'imau ile Fa'amago | <1.00% |
Le mama nofofua | <1.00% |
Metala mamafa | <20ppm |
Alaleo Infrared | E tusa ai ma le Fauga |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | Intermediate / Le mama o Irbesartan (CAS: 138402-11-6) |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
Cyano-Irbesartan (CAS: 138401-24-8) o se vaeluaga poʻo le mama o Irbesartan (CAS: 138402-11-6).Irbesartan o le angiotensin II (Angiotensin II, Ang II) fa'ainitaneti talitali.Angiotensin II receptors ua vaevaeina i ni ituaiga se lua: AT1 ma AT2.Ua poloka e Irbesartan le tali atu o le AT1 o AnglI.E mafai ona taofia le liua o le Ang i le Ang, e mafai ona faʻalavelave faʻapitoa i le angiotensin-liliu enzyme 1 receptor (AT1).Ole a'afiaga ole AT1 e 8500 taimi ile AT2.E mafai ona filifili le poloka le fusifusia o le Ang ma le AT1 receptor e ala i le Taofia vasoconstriction ma le tuʻuina atu o le aldosterone, e mafua ai le aʻafiaga o le hypotensive.O lenei oloa e le taofia ai le angiotensin converting enzyme (ACE), renin, isi hormone receptors, e le taofia foʻi ala ion e fesoʻotaʻi ma tulafono faatonutonu o le toto ma le paleni sodium.E mafai foi e Irbesartan ona faʻaitiitia le toe faʻaleleia o le eletise o le myocardium, ma faʻaitiitia ai le maliu o tagata mamaʻi e maua i le toto maualuga.O le taimi nei o le vailaʻau sili ona aoga mo togafitiga o le toto maualuga ma faʻamaʻi cardiovascular.