Dantrolene Sodium Salt Hydrate CAS 14663-23-1 API Falegaosi Tulaga Maualuga
Tuuina atu ma le mama maualuga ma le mautu lelei
Igoa Vailaau: Dantrolene Sodium Salt Hydrate
CAS: 14663-23-1
Skeletal Muscle Relaxant.Fa'agata Alaala Calcium
API Tulaga Maualuga, Gaosiga Fa'apisinisi
| Igoa Vailaau | Dantrolene Sodium Salt Hydrate |
| Synonyms | 1-[5-(4-Nitrophenyl)furfurylideneamino]hydantoin Sodium Salt Hydrate |
| Numera CAS | 14663-23-1 |
| CAT Numera | RF-API78 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i le selau Kilograms |
| Fuafua mole | C14H11N4NaO5 |
| Molecular Weight | 338.25 |
| Solubility | Solu i le DMSO |
| Tulaga Va'a | La'uina i lalo ole vevela ole ambient |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Samasama-Muliuli i Lanumu Crystalline Powder.Leai se fa'amaoniga vaaia o le fa'aleagaina e mea mai fafo |
| Faailoaina A | Le IR absorption (197K) |
| Faailoaga B | O le taimi fa'atumauina o le tumutumu tele i le chromatogram o le sauniuniga su'ega e fetaui ma lena i le chromatogram o le sauniuniga masani, e pei ona maua i le su'ega. |
| Faailoaina C | Faʻafeiloaʻi manaʻoga o le suʻega afi mo le Sodium (191) |
| Faailoaga D | Vaega 1: O se pa'epa'e tele, pa'epa'e, ma'a tioata ua faia Vaega 2: E le mou atu le pa Vaega 3: E solo atoa le sua Vaega 4: E leai se maa e faia |
| Suavai (e KF) | 14.5%~17.0% |
| Lapo'a La'au | 90% itiiti ifo i le 200um |
| Su'ega | 90.0% ~ 96.0% o le C14H10N405 i luga ole fa'avae anhydrous |
| Mea Fa'atatau | (HPLC, Area%) |
| Fa'atatau A | ≤0.15% |
| Fa'atatau B | ≤0.50% |
| Fa'atasiga Fa'atasi C | ≤0.30% |
| Solvents totoe | |
| Ethanol | ≤2000ppm |
| Methanol | ≤2000ppm |
| Acetone | ≤2000ppm |
| DMF | ≤620ppm |
| Metala mamafa | ≤10ppm |
| Ola Fa'asa | 2 Tausaga |
| Tulaga Su'ega | United States Pharmacopoeia (USP) |
| Fa'aoga | Skeletal Muscle Relaxant.Fa'agata Alaala Calcium |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
O le Dantrolene Sodium Salt Hydrate (CAS 14663-23-1), o se tama'i mole mole fa'atosina o le Ryanodine fa'afeagai fa'afeagai ma se fa'ainitaneti ala Calcium.O le Dantrolene Sodium Salt o se mea e faʻamalieina ai maso o le skeletal, lea e faʻalavelaveina ai le Ca 2 + i totonu o le tino mai le sarcoplasmic reticulum.O le poloka o le Ca2 + faʻasaʻo mai le sarcoendoplasmic reticulum, e matua fesoʻotaʻi ma le faʻamalosi ma le faʻamalosi o maso, faʻatupuina ai se aafiaga faʻamalieina maso faʻatasi ma Dantrolene.O le neurotoxicity o loʻo faʻaalia e le faʻaogaina o le glutamate e fesoʻotaʻi ma le maualuga o le maualuga o le cytoplasmic Ca2 + maualuga, ma o le Dantrolene ua faʻaalia e pei o se neuroprotective agent e faasaga i le neurotrasmitter-induced excitotoxicity.Dantrolene, Sodium Salt o se inhibitor o RyR-1 ma RyR-3.
