DAPT (GSI-IX) CAS 208255-80-5 γ-Secretase Inhibitor Assay >98.0% (HPLC) Falegaosimea
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua o DAPT (GSI-IX) (CAS: 208255-80-5) faʻatasi ai ma le maualuga, γ-Secretase Inhibitor.Ruifu Chemical o lo'o tu'uina atu se fa'asologa o amino acids ma mea e maua mai ai.E mafai ona matou tuʻuina atu i le lalolagi atoa le tuʻuina atu, laʻititi ma tele aofaʻi avanoa.Fa'atau DAPT,Please contact: alvin@ruifuchem.com
| Igoa Vailaau | DAPT |
| Synonyms | GSI-IX;γ-Secretase Inhibitor IX;gamma-Secretase Inhibitor;LY-374973;(3,5-Difluorophenylacetyl)-Ala-Phg-OtBu;(3,5-Difluorophenylacetyl)-L-Alanyl-L-2-Phenylglycine tert-Butyl Ester;N-[N-(3,5-Difluorophenacetyl)-L-Alanyl]-S-Phenylglycine t-Butyl Ester;(2S)-N-[2-(3,5-Difluorophenyl)acetyl]-L-Alanyl-2-Phenyl-glycine 1,1-Dimethylethyl Ester |
| Tulaga Fa'asoa | E tele |
| Numera CAS | 208255-80-5 |
| Fuafua mole | C23H26F2N2O4 |
| Molecular Weight | 432.47 |
| Malosi | 1.213 g/cm3 |
| Lisi Lisi | 142.0~146.0 ℃ |
| Ma'ale'ale | Ma'ale'ale vevela |
| Solubility | Solu i le DMSO |
| Temp. | Teu i le 2-8 ℃ |
| COA & MSDS | Avanoa |
| Fa'ailoga | Ruifu Chemical |
| Fa'amatalaga Saogalemu | 24/25 - Aloese mai le fa'afeso'ota'i ma le pa'u ma mata. | ||
| WGK Siamani | 3 | HS Code | 2922491990 |
| Aitema | Tulaga Fa'atonu | I'uga |
| Fa'aaliga | Pa'u Pa'epa'e po'o le Pa'epa'e Pa'epa'e | Fa'atatau |
| Ma'imau ile Fa'amago | <0.40% | 0.21% |
| Toega i luga o le mumu | <0.40% | 0.20% |
| Metala mamafa (pei o le Pb) | ≤20ppm | <20ppm |
| Su'ega / Su'esu'ega Metotia | >98.0% (HPLC) | 98.62% |
| Carbon e ala ile Elemental Analysis | 62.1~64.1% | Fa'atatau |
| Nitrogen e ala ile Elemental Analysis | 6.20-6.70% | Fa'atatau |
| Alaleo Infrared | E tusa ma le Fauga | Fa'atatau |
| NMR Alaleo | E tusa ma le Fauga | Fa'atatau |
| Fa'ai'uga | Lenei Oloa e ala ile Asiasiga E tusa ai ma le Enterprise Standard | |
| Ola Fa'asa | 24 Masina Mai le Aso Gauai pe a teu lelei | |
afifi: Fa'ato'aga Fa'alili, Ato pepa alumini, 25kg/Cardboard Drum, pe tusa ai ma mana'oga o tagata fa'atau.
Tulaga teuina:Teu i totonu o koneteina fa'amaufa'ailoga i le malulu, mago (teu i le 2-8 ℃) ma faleteuoloa fa'a'avevela mai mea e le fetaui.Puipui mai le malamalama ma le susu.
Fa'afefea ona Fa'atau?Fa'amolemole fa'afeso'ota'iDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Tausaga Aafiaga?E sili atu nai lo le 15 tausaga o le poto masani i le gaosiga ma le auina atu i fafo o le tele o tulaga maualuga o vailaʻau faʻapitoa poʻo vailaʻau lelei.
Maketi Autu?Faʻatau atu i maketi i totonu o le atunuʻu, Amerika i Matu, Europa, Initia, Korea, Iapani, Ausetalia, ma isi.
Tulaga lelei?Tulaga maualuga, tau taugofie, auaunaga faʻapolofesa ma lagolago faʻapitoa, vave tuʻuina atu.
Tulaga leleiFaamautinoaga?Fa'atonuga lelei faiga.O meafaigaluega faʻapitoa mo suʻesuʻega e aofia ai le NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Fa'ata'ita'iga?O le tele o oloa e maua ai faʻataʻitaʻiga e leai se totogi mo le iloiloga lelei, o tau o felauaiga e tatau ona totogi e tagata faʻatau.
Fale Su'etusi?Fa'afeiloa'i su'etusi falegaosimea.Fa'amolemole fai se taimi vave.
MOQ?Leai MOQ.Laititi oka e talia.
Taimi Tiliva? Afai o loʻo i totonu o faʻatauga, e tolu aso e faʻamaonia le tuʻuina atu.
Felauaiga?E ala ile Express (FedEx, DHL), ile Air, ile Sea.
Pepa?A maeʻa le faʻatau atu auaunaga: COA, MOA, ROS, MSDS, ma isi mea e mafai ona tuʻuina atu.
Tulaga Fa'apitoa?E mafai ona tu'uina atu au'aunaga tu'ufa'atasiga fa'apitoa e fetaui lelei ma au su'esu'ega mana'oga.
Tulaga Totogi?Proforma invoice o le a lafo muamua pe a maeʻa le faʻamaoniga o le poloaiga, faʻapipiʻi a matou faʻamatalaga faletupe.Totogi e le T / T (Telex Transfer), PayPal, Western Union, ma isi.
DAPT (GSI-IX) (CAS: 208255-80-5), o se inhibitor malosi ma faʻapitoa ole γ-secretase.O le DAPT o se faʻalavelave ole γ-secretase (IC50 i neu muamua a le tagata = 115 nM mo le Aβ atoa poʻo le 200 nM mo Aβ42 faʻapitoa).O le faʻaogaina tautala a le DAPT ua faʻaalia e faʻaitiitia ai le maualuga o le Aβ i le faiʻai, sua o le cerebrospinal ma le plasma mai isumu ma isumu.Ua poloka e le DAPT le faailoilo o le Notch lea e siitia ai le eseesega o neuronal o sela muamua.Faʻaleleia sela iPS e aunoa ma le oncogenes KLF4 ma CMYC5.Selulu e mafai ona maua.O loʻo faʻaaogaina le DAPT i le suʻesuʻeina o le β-amyloid formation.Ua faʻaalia le DAPT e taofia ai le faʻailoga o le Notch i suʻesuʻega o faʻamaʻi autoimmune ma lymphoproliferative, e pei o le ALPS ma le lupus erythematosus, faʻapea foʻi ma le tuputupu aʻe o le kanesa, angiogenesis, ma le faʻavasegaina o sela o le pluripotent stem cell.Taofi le fa'ailoga Notch in vitro.Faʻasaʻo le aofaʻi o le Aβ ma le Aβ42 gaosiga i aganuʻu muamua a le tagata (o le IC50 o le 115 ma le 200 nM, i le faasologa) e leai se aʻafiaga i APPα ma APPβ.Pa puipui toto-faiai e mafai ona sao.3D Growth matrix component ma vaega ole cerebral organoid differentiation media.
