Despropionyl Ramelteon Hydrochloride CAS 196597-80-5 Mama>98.0% (HPLC)
Ta'ita'i Gaosi ma Fa'atau
Intermediates o Ramelteon:
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-tasi CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
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| Igoa Vailaau | (S)-2-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-yl)ethylamine Hydrochloride |
| Synonyms | Despropionyl Ramelteon Hydrochloride;(S)-2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride;(S)-2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine HCl;Ramelteon Le mama 15 HCl;Ramelteon Amine Le mama |
| Numera CAS | 196597-80-5 |
| CAT Numera | RF2888 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
| Fuafua mole | C13H17NO.HCl |
| Molecular Weight | 239.74 |
| Lisi Lisi | 270 ℃ |
| Solubility i le Vai | Solu i Chloroform, Dichloromethane, Ethyl Acetate, Methanol |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pa'epa'e i le Pa'epa'e Pa'epa'e Malosi |
| Mama / Suʻesuʻega Metotia | >98.0% (HPLC) |
| Ma'imau ile Fa'amago | <1.00% |
| Le mama nofofua | <1.00% |
| Aofa'i Fa'aleaga | <2.00% |
| 1 H NMR Alaleo | Osi ma le Fauga |
| Tulaga Su'ega | Pisinisi Tulaga |
| Fa'aoga | Intermediate of Ramelteon (CAS: 196597-26-9) |
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(S)-2-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-yl)ethylamine Hydrochloride, ua lauiloa foi o Despropionyl Ramelteon Hydrochloride (CAS: 196597-80-5 ) o se vaeluagalemu o Ramelteon (CAS: 196597-26-9).Ramelteon (TAK-375) o se tala fou melatonin receptor agonist mo tagata MT1 ma MT2 faʻafeiloaʻi ma moa foebrain tali melatonin ma Ki o 14 pM, 112 pM ma 23.1 pM, faasologa.O le mole mole melatonin na fa'apena ona suia e ala i le suia o le nitrogen o le mama indole ma se kaponi e maua ai se mama indane ma e ala i le fa'aofiina o le vaega 5-methoxyl i totonu o le mama indole i se mama furan sili atu.O le filifilia o le Ramelteon e maua mo le MT1 e valu taimi e sili atu nai lo le MT2 tali.E le pei o le melatonin, e sili atu le aoga i le amataina o le moe (MT1 gaioioiga) nai lo le toe fetuutuunai o le pao o le circadian (MT2 gaoioiga).E foliga mai e sili atu le aoga nai lo le melatonin ae leai se aoga nai lo le benzodiazepines o se hypnotic.O le mea taua, o lenei vaila'au e leai se noataga o vaisu (e le o se mea e pulea).O se taunuuga, talu ai nei na faʻamaonia mo togafitiga o le le mautonu.
