Diethylphosphonoacetic Acid CAS 3095-95-2 Mama>99.5% (HPLC) Afatinib Dimaleate Intermediate Factory

Fa'amatalaga Puupuu:

Igoa vaila'au: Diethylphosphonoacetic Acid

CAS: 3095-95-2

Mama: >99.5% (HPLC)

Fa'aaliga: Suavai e leai ni lanu

Intermediate of Afatinib Dimaleate (CAS: 850140-73-7)

Tulaga Maualuga, Gaosiga Fa'apisinisi

E-Mail: alvin@ruifuchem.com

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Meatotino tau vailaau:

Igoa Vailaau	Diethylphosphonoacetic Acid
Synonyms	2-(Diethoxyphosphoryl)acetic Acid;(Diethoxyphosphinyl)acetic Acid;Diethyl Carboxymethylphosphonate;NSC 272281
Numera CAS	3095-95-2
CAT Numera	RF-PI2024
Tulaga Fa'asoa	I Fa'atauga, Gaosi Gaosi 30MT/Masina
Fuafua mole	(C2H5O)2P(O)CH2CO2H
Molecular Weight	196.14
Fa'apuna	150 ℃/0.05 mmHg (malamalama)
Malosi	1.220 g/mL ile 25℃ (malamalama)
Fa'asino Upu	n20/D 1.445 (ma.)
Fa'ailoga	Ruifu Chemical

Fa'amatalaga:

Aitema	Fa'amatalaga
Fa'aaliga	Suavai le lanu
Fa'ailoga (HPLC)	O le taimi fa'atumauina o le tumutumu autu na maua mai le fa'ata'ita'iga o lo'o i totonu ole 5% ole fa'ata'ita'iga fa'asino.
Mama / Suʻesuʻega Metotia	>99.5% (HPLC)
Alaleo Infrared	E tusa ma le Fauga
Proton NMR Alaleo	E tusa ma le Fauga
Susū (KF)	<0.50%
Aofa'i Fa'aleaga	<0.50%
Tulaga Su'ega	Pisinisi Tulaga
Fa'aoga	Intermediate of Afatinib Dimaleate (CAS: 850140-73-7)

Paket & Teuina:

afifi: Fluorinated Bottle, 25kg/ Drum, pe tusa ai ma manaoga o tagata faatau

Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu

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Talosaga:

Diethylphosphonoacetic Acid (CAS: 3095-95-2), E galue e pei o se nucleophile mo tali faaopoopo nucleophilic mo le tuufaatasia o allene epoxides Reactant mo: Stereoselectivity suʻesuʻega o le tali a Staudinger;Enantioselective fa'avaeina o diols e ala ile epoxidation ma fa'amama fa'afefe;tali a Horner-Wadsworth-Emmons;Chelation mamao pulea Aialani-Claisen toe fetuunaiga;Ugi-Dieckmann tali mo le tuufaatasia o le tetramic acid derivatives;Fa'aoga e fai ai ni mea fa'alava ole phosphonoester mo fa'a'avega HEW intramolecular.Diethylphosphonoacetic Acid o se vaeluaga ole Afatinib Dimaleate (CAS: 850140-73-7).Afatinib Dimaleate na faʻamaonia e le US Food and Drug Administration (FDA) i le 2013 mo le togafitia o le kanesa o le mama sela (NSCLC).Aemaise lava, na faʻamaonia mo tagata mamaʻi o loʻo maua i metastatic NSCLC tuma o loʻo i ai le epidermal growth factor receptor (EGFR) exon deletions poʻo le exon 21 suiga.O le Afatinib Dimaleate o se inhibitor faʻamalosi ole ErbB tyrosine kinases (tyk), lea e faʻaitiitia ai le faʻailoga ErbB e ala i le faʻaogaina o nofoaga faʻapipiʻi EGFR tyk.