Entecavir Monohydrate CAS 209216-23-9 falegaosimea API High Quality Antiviral Hepatitis B Fa'ama'i Ata Fa'aalia

Entecavir Monohydrate CAS 209216-23-9 falegaosimea API Tulaga maualuga Fa'ama'i Hepatitis B.

Fa'amatalaga Puupuu:

Igoa vaila'au: Entecavir Monohydrate

CAS: 209216-23-9

Fa'aaliga: Pa'epa'e Pa'epa'e po'o Toeitiiti Pa'epa'e Pa'u tioata

Antiviral vailaʻau faʻaaogaina i le togafitiga o Faʻamaʻi Hepatitis B

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Fa'amatalaga:

Tuuina atu a le Faumea ma le Mamalu Maualuga ma le Tulaga Lelei
Igoa vaila'au: Entecavir Monohydrate
CAS: 209216-23-9
Fa'aaogaina ile togafitiga ole Fa'ama'i Hepatitis B
API Tulaga Maualuga, Gaosiga Fa'apisinisi

Meatotino tau vailaau:

Igoa Vailaau	Entecavir Monohydrate
Synonyms	Entecavir Hydrate;9-[(1S,3R,4S)-4-Hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]guanine Monohydrate
Numera CAS	209216-23-9
CAT Numera	RF-API79
Tulaga Fa'asoa	I Fa'atauga, Oloa Fua e O'o i le selau Kilograms
Fuafua mole	C12H17N5O4
Molecular Weight	295.3
Lisi Lisi	>220℃
Malosi	1.81
Tulaga Va'a	La'uina i lalo ole vevela ole ambient
Fa'ailoga	Ruifu Chemical

Fa'amatalaga:

Aitema	Fa'amatalaga
Fa'aaliga	Pa'epa'e po'o le Toeitiiti Pa'epa'e Pa'u tioata
Solubility	Solufua Saoloto i le Dimethylformamide, Solu Teisi i le Vai, Ethanol ma Methanol
Faailoaina IR	Ole alaleo ole fa'ata'ita'iga e fetaui ma le tulaga fa'asino
Fa'ailoga HPLC	O le taimi fa'atumauina o le fa'ata'ita'iga fa'ata'ita'iga e fetaui ma le tulaga fa'asino
Suavai (e KF)	5.5%~6.5%
Fa'asinomaga Fa'ailo	+24.0° i le +30.0° (DMF: MeOH=1:1 C=1%) (i luga o mea e leai ni vai)
Toega i luga o le mumu	≤0.10%
Mea Fa'atatau
Furoentecavir	≤0.10%
Entecavir 1-Epimer	≤0.10%
Entecavir 3-Epimer	≤0.10%
8-Methyoxy Entecavir	≤0.10%
Entecavir 4-Epimer	≤0.10%
8-Hydroxy Entecavir	≤0.10%
4-Dimethylsilyl Entecavir	≤0.10%
Entecavir Related Compound A	≤0.10%
So'o se mea le mama e le o ta'ua	≤0.10%
Aofa'i Fa'aleaga	≤0.30%
Solvents totoe
Methanol	≤600ppm
Dichloromethane	≤300ppm
Ethyl Acetate	≤1000ppm
Tetrahydrofuran	≤720ppm
Toluene	≤890ppm
Benzyl Chloride	≤1000ppm
Benzyl Alcohol	≤1000ppm
Tapulaa Microbial
Faitauga Aerobic Aofa'i	≤100cfu/g
Faafefete ma Molds	≤10cfu/g
Escherichia Coli	E le tatau ona iloa
Metala mamafa	≤10ppm
Su'ega	98.0% ~ 102.0% (HPLC; i luga o le anhydrous faavae)
Lapo'a La'au	95% o vaega e tatau ona i totonu ole 125um
Tulaga Su'ega	Atina'e Atina'e;United States Pharmacopoeia (USP) Standard
Fa'aoga	Antiviral vailaʻau faʻaaogaina i le togafitiga o Faʻamaʻi Hepatitis B

Paket & Teuina:

afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.

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Talosaga:

O le Entecavir Monohydrate (CAS 209216-23-9) ose vaila'au fa'ama'i fa'ama'i e fa'aaogaina i le togafitia o fa'ama'i pipisi o le Hepatitis B Virus (HBV).Entecavir Monohydrate o se nucleoside analog (sili atu faapitoa, o se guanine analogue) e taofia ai le faʻaliliuina o le faʻaliliuga, DNA replication ma transcription i le vira.Ose ituaiga fou ole cyclopentyl acyl guanosine anti-Hepatitis B fa'ama'i fa'ama'i ma ona a'afiaga fa'afoma'i e tutusa ma le Entecavir.O lo'o fa'aogaina ile falema'i ile togafitiga ole Hepatitis B fa'ama'i matutua o lo'o iai fa'asologa fa'ama'i viral, fa'ateleina le serum transaminase ALT po'o manu'a gaogao na fa'aalia mai le fa'asologa o le ate.Entecavir Monohydrate o se inhibitor malosi ma filifilia o le HBV, faʻatasi ai ma le EC50 o le 3.75 nM i le HepG2 cell.O le Entecavir o se fa'ailoga fa'aliliuga fa'aliliu.E puipuia ai le Fa'ama'i Hepatitis B (HBV) mai le fa'ateleina ma fa'aitiitia le aofa'i o siama i totonu o le tino.