Epalrestat CAS 82159-09-9 Mama>99.5% (HPLC) Falegaosimea
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua o Epalrestat (CAS: 82159-09-9) faʻatasi ai ma le maualuga.Ruifu Chemical e mafai ona tuʻuina atu i le lalolagi atoa, tau faʻatauvaʻa, laʻititi ma tele aofaʻi avanoa.Fa'atau Epalrestat,Please contact: alvin@ruifuchem.com
Igoa Vailaau | Epalrestat |
Synonyms | Epalrest;ONO-2235;Aepeth;Kinedak;Sorbistat;(5Z)-5-[(2E)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-Thiazolidineacetic Acid;2-[(5Z)-5-[(E)-3-Phenyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic Acid;(E,E)-2-[5-(2-Methyl-3-phenyl-prop-2-enylidene)-4-oxo-2-sulfanylidene-thiazolidin-3-yl]acetic Acid |
Tulaga Fa'asoa | I Fa'atauga, Mass Production |
Numera CAS | 82159-09-9 |
Fuafua mole | C15H13NO3S2 |
Molecular Weight | 319.39 g/mol |
Lisi Lisi | 222.0 i le 226.0 ℃ |
Malosi | 1.43±0.10g/cm3 |
Solubility | DMSO 2 mg/mL Vai <1 mg/mL Ethanol <1 mg/mL |
Temp. | Nofoaga malulu ma mago (-20℃) |
COA & MSDS | Avanoa |
Vaega | API |
Fa'ailoga | Ruifu Chemical |
Aitema | Tulaga Fa'atonu | I'uga |
Fa'aaliga | Lanu moli i Lanumu Mumu Crystalline Powder | E usitaia |
Fa'ailoaga | E tutusa ma le HPLC taimi fa'amauina o tulaga masani | Pasia |
Lisi Lisi | 222.0 i le 226.0 ℃ | 222.4~224.3 ℃ |
Ma'imau ile Fa'amago | <0.50% | 0.04% |
Toega i luga o le mumu | <0.20% | 0.03% |
Metala mamafa (Pb) | ≤20ppm | <20ppm |
Aofa'i Fa'aleaga | ≤0.50% | 0.20% |
Mama / Suʻesuʻega Metotia | >99.5% (HPLC) | 99.8% |
Alaleo Infrared | E tusa ma le Fauga | E usitaia |
Fa'ai'uga | Ua uma ona fa'ata'ita'iina le oloa ma fa'amalieina fa'atonuga |
afifi:Fagu, Ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i le malulu ma mago (-20 ℃) faleteuoloa ese mai mea e le fetaui.Puipui mai le malamalama ma le susu.
Va'a:Tu'u atu i le lalolagi atoa e FedEx / DHL Express.Tuuina atu vave ma faatuatuaina tiliva.
Fa'afefea ona Fa'atau?Fa'amolemole fa'afeso'ota'iDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Maketi Autu?Faʻatau atu i maketi i totonu o le atunuʻu, Amerika i Matu, Europa, Initia, Korea, Iapani, Ausetalia, ma isi.
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UN IDs 2811
WGK Siamani 3
RTECS XJ5131855
Vasega o Tulaga Lamatia 6.1
Vaega fa'apipi'i II
Epalrestat (CAS: 82159-09-9) o le lona lua aldose reductase inhibitor e faʻalauiloaina i le lalolagi atoa ma le muamua e faʻalauiloa i Iapani.Epalrestat ua faʻaalia mo togafitiga o le neuropathy o le maʻisuka.O loʻo suʻesuʻeina foʻi mo le maʻisuka retinopathy ma nephropathy.Epalrestat o le aldose reductase inhibitor ma le IC50 o le 72 nM.
O le Epalrestat e taofia le Aldose Reductase (AR) o loʻo aʻafia i le faʻatapulaʻaina o le laasaga i le liua o le kulukose i le sorbitol i lalo o tulaga hyperglycemic.Aldose reductase ua avea ma taulaiga o le tele o suʻesuʻega faʻapitoa e togafitia ai le neuropathy maʻisuka ma le retinopathy.Epalrestat o se vailaʻau faʻamaonia i Iapani ma Initia, faʻaaogaina mo togafitiga o le neuropathy o le maʻisuka.
Epalrestat e faʻaaogaina e puipuia ai, faʻaleleia, ma togafitia le neuropathy lautele (numbness, tiga), vibrational paresthesia, ma le faʻalavelave fatu e fesootaʻi ma le maʻisuka.
O le Epalrestat e avea ma sui o fualaau faasaina e faʻaitiitia ai le faʻaputuina o le fructose ma le sorbitol e ala i le faʻafefeina o le aldose reductase, toe faʻafoʻisia Na + -K + -ATPase ma le inositol, faʻateleina le NO i totonu o sela endothelial, faʻalavelaveina le protein kinase C ala faʻailoga, endothelial cell adhesion, maualuga kulukose- mediated neutrophil ma endothelial adhesion factor expression ma faʻaitiitia le carboxymethyl lysine oloa i tagata maʻi suka, ma togafitia faʻamaʻi e pei o le maʻisuka ma ona faʻalavelave.