Erlotinib Hydrochloride CAS 183319-69-9 Mama>99.0% (HPLC)

Fa'amatalaga Puupuu:

Igoa vaila'au: Erlotinib Hydrochloride

Synonyms: Erlotinib HCl;Tarceva

CAS: 183319-69-9

Mama (HPLC): >99.0%

Fa'aaliga: Pa'epa'e i le Pa'u Pa'epa'e Pa'epa'e

Fa'afeso'ota'i: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Fa'amatalaga:

Ta'ita'i ta'ita'i ma fa'atau oloa Erlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis(2-Methoxyethoxy)-3H-Quinazolin-4-tasi CAS 179688-29-0
Please contact: alvin@ruifuchem.com

Meatotino tau vailaau:

Igoa Vailaau	Erlotinib Hydrochloride
Synonyms	Erlotinib HCl;Tarceva;CP-358774 Hydrochloride;6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline Hydrochloride;N-(3-Ethynylphe nyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine HCl
Numera CAS	183319-69-9
CAT Numera	RF-PI2242
Tulaga Fa'asoa	I Fa'atauga, Oloa Fua e O'o i Tone
Fuafua mole	C22H24ClN3O4
Molecular Weight	429.90
Fa'ailoga	Ruifu Chemical

Fa'amatalaga:

Aitema	Fa'amatalaga
Fa'aaliga	Pa'epa'e i le Pa'u Pa'epa'e Pa'epa'e
Fa'ailoaga	A: IR: Faʻatatau i Faʻamatalaga Alaleo B: HPLC: Fa'atatau ile Fa'asinomaga RT
Solubility	E matua'i solu i le vai, solu teisi i le Methanol ma e le mafai ona solu ile Acetonitrile, Acetone, Ethyl Acetate ma Hexane.
Lisi Lisi	223.0~229.0 ℃
Ma'imau ile Fa'amago	<0.50%
Toega i luga o le mumu	<0.20%
Metala mamafa	<20ppm
Le mama nofofua	<0.50%
Aofa'i Fa'aleaga	<1.00%
Solvents totoe
Pyridine	<4000ppm
Chloroform	<4000ppm
DMF	<3000ppm
Mama / Suʻesuʻega Metotia	>99.0%
Su'ega / Su'esu'ega Metotia	98.5%~101.0% (Fa'amauina i luga ole Anhydrous Basis)
Tulaga Su'ega	Pisinisi Tulaga
Fa'aoga	API

Paket & Teuina:

afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau

Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu

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Talosaga:

Erlotinib Hydrochloride (CAS: 183319-69-9) o se mole laʻititi o le epidermal growth factor receptor tyrosine kinase reversible inhibitor, e masani ona faʻaaogaina i le togafitiga o le kanesa o le mama i le lotoifale poʻo le metastatic ma le laina lona lua poʻo le tolu laina togafitiga o. kanesa pancreatic.Erlotinib Hydrochloride na fa'amaonia ia Novema, 2004, mo le togafitia o le kanesa o le mama e le o ni sela laiti.E a'afia i le vasega lava e tasi e pei o Gefitinib, o le isi quinazoline ua fa'amaonia mo le togafitia o le kanesa o le mama, ae fa'atasi ai ma le fa'aleleia atili o mea tau vaila'au.O le mole mole na afua mai e le Pfizer ma le atinaʻe na amataina i le galulue faʻatasi ma le OSI, lea na faʻaaogaina ai aia tatau i le vailaʻau ina ua tuʻufaʻatasia le Pfizer ma Warner Lambert.Mulimuli ane, na alu Genentech/Roche i laisene laiseneina ma le OSI e atiaʻe ma maketiina le vailaʻau i le US ma le lalolagi atoa.Filifiliga epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor.Atineoplastic.Erlotinib Hydrochloride o se inhibitor HER1 / EGFR ma IC50 o le 2 nM.Erlotinib HCl o loʻo maua e pei o le 25-, 100-, ma le 150-mg tablets mo le faʻatonuga.