Ethyl (S)-4-Chloro-3-hydroxybutyrate CAS 86728-85-0 Atorvastatin Calcium Intermediate
Igoa Vailaau | Ethyl (S)-4-Chloro-3-hydroxybutyrate |
Synonyms | (S)-4-Chloro-3-hydroxybutyric Acid Ethyl Ester |
Numera CAS | 86728-85-0 |
CAT Numera | RF-PI139 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C6H11ClO3 |
Molecular Weight | 166.6 |
Malosi | 1.19 g/mL ile 25℃ (malamalama) |
Fa'asino Upu | n20/D 1.453 (me.) |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Suavai e le lanu samasama samasama |
Mama / Suʻesuʻega Metotia | ≥98.0% (GC) |
Susū (KF) | ≤0.50% |
Ethyl-4-Chloro Aceto Acetate | ≤0.50% |
Tulaga Su'ega | Enterprise Standard |
Fa'aoga | Pharmaceutical Intermediate;Fa'asoa fa'aletino |
Ethyl (S)-4-Chloro-3-hydroxybutyrate (CAS: 86728-85-0)
Metotia o au'ili'iliga
Fa'amatalaga
Ave pe tusa ma le 10ml fa'ata'ita'iga ile ipu tioata mama ma mago ma siaki.
Ta'amilosaga fa'apitoa
Fa'asolo sa'o e tusa ma le 1.0g o le fa'ata'ita'iga ile 100ml volumetric flask ma fa'amavae i totonu10 ml o le chloroform, ona faʻafefiloi lea i le chloroform i le 100ml ma faʻafefiloi.
Fua le suiga mata'utia o le su'ega faataitai ile 25ºC ma le 589nm umi galufa'atatau le suiga ma'oti e tusa ai ma le fua fa'atatau.
[a]25D = (v×a)/[w×(1-b)]
[a]25D: o le suiga patino o le suʻegafa'ata'ita'iga;α: o le taamilosaga ua matauina i totonutikeri tulimanu;w: fa'ata'ita'iga mamafa (g);
v: voluma (mL);
e: vai (%)
Mama (e GC)
Tulaga Chromatographic: O le chromatography Gas ua faʻapipiʻiina i le mumuionization detector
Koluma: SE-54, 30m×0.35mm×0.25µm
O le vevela o le ogaumu: Muamua vevela 120℃, Taofi le taimi mo le 2min
Ramp: 20℃/min
Temp: 250 ℃, Taofi le taimi mo le 2min
Injector vevela: 250 ℃
Su'e vevela: 250℃(FID)
Volume tui: 0.2µl
Fa'ata'ita'iga fofo: fa'asusu le 1ml A4 ma le 1ml acetone.
Faiga: Tu'i le 0.2µl o le acetone e avanoa ma fa'amaumau le chromatogram.I lechromatogram e maua mai le fa'afefiloi e le tatau ona i ai se fa'alavelave i letaimi taofi o le tumutumu autu ma le tumutumu le mama.Ona tui lea o le vaifofo faataitai i totonufa'alua i le chromatograph ma fa'amaumau le chromatogram.Lipoti le Mama ofa'ata'ita'iga e ala i le fa'avasegaina o le eria.
afifi: Fagu, paelo, 25kg / paelo, pe tusa ai ma manaoga o tagata faatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua ma le tuʻuina atu o le Ethyl (S) -4-Chloro-3-hydroxybutyrate (CAS: 86728-85-0) faʻatasi ai ma tulaga maualuga, o se vaeluaga masani i le tuʻufaʻatasia o Atorvastatin. Calcium (CAS: 134523-03-8).
Atorvastatin Calcium (CAS: 134523-03-8) [igoa fefaʻatauaʻiga: Lipitor] e masani ona faʻaalia mo togafitiga o maʻi cardiovascular ma dyslipidemia ona o lona aʻafiaga i le faʻaitiitia o le cholesterol i le toto.Atorvastatin e galue muamua i le ate.O le fa'aitiitia o le maualuga ole cholesterol ile ate e fa'ateleina ai le fa'aogaina ole cholesterol ma fa'aitiitia le maualuga ole cholesterol ile plasma.Lipitor, talu mai le 1996, ua avea ma vailaʻau sili ona faʻatau atu i le lalolagi i lena taimi.