Etravirine TMC-125 CAS 269055-15-4 Su'esu'ega ≥99.0% (HPLC) API Falegaosi Mamalu Maualuga
Faumea e maualuga le mama ma mautu lelei
Igoa vaila'au: Etravirine (TMC-125)
CAS: 269055-15-4
API Tulaga Maualuga, Gaosiga Fa'apisinisi
Igoa Vailaau | Etravirine |
Synonyms | TMC-125 |
Numera CAS | 269055-15-4 |
CAT Numera | RF-API54 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C20H15BrN6O |
Molecular Weight | 435.28 |
Malosi | 1.439 g/cm3 |
Tulaga Va'a | I lalo ole Temperature Ambient |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'u Pa'epa'e Malosi |
Fa'ailoaga | Saunia e IR, HPLC |
Lisi Lisi | 211.0~216.0 ℃ |
Suavai Suavai | ≤0.50% |
Toega i luga o le mumu | ≤0.20% |
Metala mamafa | ≤20ppm |
So'o se Fa'aleaga Ta'itasi | ≤0.50% |
Aofa'i Fa'aleaga | ≤1.0% |
Su'ega | ≥99.0% (HPLC) |
Tulaga Su'ega | Pisinisi Tulaga |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
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Etravirine (TMC-125) (CAS 269055-15-4) o se faʻasologa lona lua e le o nucleoside reverse transcriptase inhibitor (NNRTI) faʻaaogaina mo togafitiga o le HIV.Ua fa'ailoa mai mo le fa'aogaina fa'atasi ma isi vaila'au fa'ama'i mo le togafitia o fa'ama'i pipisi o le HIV-1 i tagata mama'i matutua e iai le fa'amaoniga o le toe faia o fa'ama'i ma fa'ama'i HIV-1 e tetee atu i NNRTI o lo'o avanoa nei ma isi vaila'au fa'ama'i.O NNRTIs, faʻatasi ai ma le nucleoside / nucleotide reverse transcriptase inhibitors (NRTIs / NtRTIs), o vaega taua ia o faʻatonuga tuʻufaʻatasia o loʻo faʻaaogaina nei e togafitia ai le HIV-1.O le NRTIs/NtRTIs e galue e ala i le tauva ma le natura nucleotide substrates o reverse transcriptase mo le tuʻufaʻatasia i le DNA viral ma mulimuli ane faʻamutaina filifili.I le faʻatusatusaga, o NNRTI e fusifusia i se nofoaga o le enzyme allosteric ma faʻalavelaveina le galuega DNA polymerase e ala i le faʻaosoosoina o suiga faʻavae i le nofoaga catalytic.
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