Fingolimod Hydrochloride CAS 162359-56-0 Mama ≥99.0% (HPLC) API Falegaosi Mamalu Maualuga
Faumea e maualuga le mama ma mautu lelei
Igoa vaila'au: Fingolimod Hydrochloride
CAS: 162359-56-0
O le Fingolimod Hydrochloride ose vaila'au fa'amaonia e le FDA mo togafitiga o le Multiple Sclerosis.
API Tulaga Maualuga, Gaosiga Fa'apisinisi
Igoa Vailaau | Fingolimod Hydrochloride |
Synonyms | Fingolimod HCl;FTY 720 |
Numera CAS | 162359-56-0 |
CAT Numera | RF-API39 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i le selau Kilograms |
Fuafua mole | C19H34ClNO2 |
Molecular Weight | 343.93 |
Lisi Lisi | 102.0~107.0°C |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e i le Pa'epa'e Pa'epa'e |
Fa'ailoaga | HPLC |
Lisi Lisi | 102.0~106.0 ℃ |
Solubility | Solu atoatoa i le Vai |
Mama / Suʻesuʻega Metotia | ≥99.0% (HPLC) |
Susū (KF) | ≤0.50% |
Toega i luga o le mumu | ≤0.20% |
Metala mamafa | ≤20ppm |
Solvents totoe | |
Dichloromethane | ≤0.05% |
Ethyl Acetate | ≤0.50% |
Ethanol | ≤0.50% |
Methanol | ≤0.30% |
Toluene | ≤0.089% |
THF | ≤0.50% |
DMF | ≤0.088% |
Mea Fa'atatau | |
Le mama nofofua | ≤0.50% |
Aofa'i Fa'aleaga | ≤1.0% |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | Mea Fa'afoma'i Gaoioiga (API) |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua ma le tuʻuina atu o Fingolimod Hydrochloride (CAS: 162359-56-0) faʻatasi ai ma le maualuga.
Fingolimod Hydrochloride o le vailaʻau tuʻu muamua muamua mo le togafitia o le tele sclerosis.O loʻo faʻaleleia lelei e le kamupani vailaʻau Novartis, ma ua faʻamaonia mo le maketiina e le US Food and Drug Administration (FDA).O le tele o le sclerosis o se fa'ama'i fa'aletonu o le neura e mafai ona mafua ai ona le maua e le tagata ma'i se lagona o le paleni, foliga mai o maso ma'i ma isi fa'aletonu o gaioiga.Fingolimod Hydrochloride o se sphingosine-l-phosphate (S1PR) faʻafeiloaʻi modulator.A maeʻa le phosphorylation, ua noatia i le s1P receptor o loʻo i luga o le lymphocyte, lea o le a suia ai le lymphocyte migration, ma faʻalauteleina sela i totonu o le tino lymphatic, ma puipuia lymphocytes mai le tuua o le tino lymphoid ma ulu atu i le sulu.O le mea lea, o le a taofia ai nei sela mai le ulufale atu i le fatugalemu o le tino (CNS), lea e ausia ai le aafiaga o le immunosuppression.