Fmoc-Gly-OH CAS 29022-11-5 Fmoc-Glycine Purity >99.0% (HPLC) Falegaosimea

Fmoc-Glycine (Fmoc-Gly-OH) (CAS: 29022-11-5) o se ituaiga N-Fmoc-puipuia o Glycine.Glycine o se amino acid e le taua.Fmoc-amino acids, faʻaaogaina i le peptide synthesis, faʻaaogaina e avea o se mea faʻapipiʻi faʻale-aganuʻu, vailaʻau vailaʻau, vailaʻau faʻasolosolo poʻo vailaʻau faʻamaʻi.
Folasaga: Fmoc-Glycine o Glycine puipuia e Fmoc.Fluorene methoxycarbonyl (Fmoc) o se vaega puipuia maaleale faavae, lea e mafai ona faaaogaina i le vai ammonia concentrated po o le dioxane-methanol-4N NaOH(30:9:1) ma piperidine, ethanolamine, cyclohexylamine, 1,4-Dioxane, pyrrolidone ma isi fofo ammonia 50% dichloromethane.I lalo ole tulaga vaivai ole alkaline e pei ole sodium carbonate po'o le sodium bicarbonate, ole vaega puipuia ole Fmoc e masani ona fa'aofiina e Fmoc-Cl po'o Fmoc-OSu.
Talosaga: Fmoc-Glycine o le Fmoc-puipuia Glycine, lea e masani ona faʻaaogaina e faʻapipiʻi ai polypeptides.Ole eseesega ole vaega ole puipuiga ole amino acid e iai se aafiaga tele ile lelei ma le gaosiga ole polypeptide synthesis.Mo se faʻataʻitaʻiga, e mafai ona faʻaogaina le Fmoc-Glycine e saunia ai se inhibitor corrosion derivative glycine, ma o le Fmoc-protecting group ma le hydrophobic umi filifili e fesoʻotaʻi atu i le Glycine mole e ala i le tali amidation, ma le heteroatom (N, O, ma isi) Poʻo. noanoa unsaturated) ma le mama bisphenyl o loo i ai π electrons ua adsorbed i luga o le uamea, ma le hydrophobic filifili umi poloka poloka vai, ina ia fausia ai se ata puipui i luga o le uamea e ausia ai le faamoemoega o le corrosion puipuiga.
Sauniuniga: Fmoc-Glycine fa'asologa fa'asologa fa'apitoa e pei ona taua i lalo: 3.0g Glycine ua solo i le 115ml o le 10% Na2CO3, fa'amalieina i le -4 ~ 0 ℃, 11.2g Fmoc-Cl fa'amavae i le 35.0ml o le acetone ma fa'aopoopo i le faiga fa'ato'alalo, a mae'a fa'aopoopo fa'atete'e, fa'aoso i le ta'ele aisa mo le 30min, ona fa'aoso lea i le vevela o le potu mo le 2.0h.Sa mata'ituina le alualu i luma ole tali ile chromatography layer manifinifi.Ina ua maeʻa le tali, 400ml o le vai na sasaa i totonu o le vai, e faʻalua faʻalua le eter, faʻamafanafana ma fetuunai i le pH2 faʻatasi ma le faʻamaʻi o le hydrochloric acid, o le tele o le paʻepaʻe paʻepaʻe na faʻafefeteina, 50 ml o le ethyl acetate na maua faatolu, anhydrous magnesium. sa fa'amago le sulfate, fa'amama le solvent i lalo o le fa'aitiitia o le mamafa, ma fa'aaoga le suau'u eter e fa'afefete e maua ai le 11.5g o Fmoc-Glycine.A maeʻa le faʻamamaina, o le mama o le oloa e 97.35% e ala ile chromatography vai maualuga.