Fmoc-Ile-OH CAS 71989-23-6 Fmoc-L-Isoleucine Purity >99.0% (HPLC) Falegaosimea

Fmoc-L-Isoleucine (Fmoc-Ile-OH) (CAS: 71989-23-6) o se isoleucine derivative, o se amino acid e le masani ai mo peptidomimetics.Fmoc-L-isoleucine o le Nα-9-fluorenylmethoxycarbonyl-amino acid.9-fluorenylmethoxycarbonyl o se vaega taua amino puipuia i le peptide synthesis.Talu ai ona o se vaega faʻavae puipuia ma e faʻamautu i tulaga e faʻaaogaina e aveese ai vaega puipuia masani, o loʻo i ai se tulaga tulaga ese i le polypeptide synthesis.Poloka faufale masani mo le fa'asologa o le peptide fa'asologa masani e mulimuli i le Fmoc-tactics.
Fmoc-amino acids, faʻaaogaina i le peptide synthesis, faʻaaogaina e avea o se mea faʻapipiʻi faʻale-aganuʻu, vailaʻau vailaʻau, vailaʻau faʻasolosolo poʻo vailaʻau faʻamaʻi.
Sauniuniga L-Isoleucine (CAS: 73-32-5) 1.05g (0.008 mol) o le malo na solo i le 10% sodium carbonate solution, L-isoleucine solid na lava le solo e ala i le faʻamalosi.I le 20 ~ 30 ℃, 9-fluorenylmethoxycarbonyl chloride (205g) solo i toluene (2 ~ 2.10) faʻaopoopo dropwise, 0.008 mol) fofo, Dropwise faaopoopo 30 ~ 60 minute, le faaiuga o le faʻaopoopoga, i le 20 ~ 30 C faʻafefe 1 ~ 8 itula, faaopoopo 30 ~ 200 ml o vai dilution, faatasi ai ma le n-butyl acetate (80 ml) sili atu 9-fluorenylmethoxycarbonyl chloride na aveesea e ala i le aveesea, o le vaega aqueous taunuuga sa acidified ma concentrated hydrochloric acid i PH = 0.5 ~ 3.5, ona aveese mai i le n-butyl acetate (80 ml), ma o le vaega o le suauu na maua na fufuluina i le vai e aveese ai le hydrochloric acid, o le vaega o le suauu na faʻatumauina e aveese ai le solvent n-butyl acetate, tioata paʻepaʻe na faʻafefeteina, faʻamago ma faʻagogo e tuʻuina atu ai le oloa. Fmoc-L-Isoleucine 2.48g, maua mai 87.9%, Liu Liu: 140.0 ~ 155.0 ℃.