Fondaparinux Sodium CAS 114870-03-0 API
Tuuina atu ma le mama maualuga ma le mautu lelei
Igoa Vailaau: Fondaparinux Sodium
CAS: 114870-03-0
O le Antithrombotic Anticoagulant, o le Factor Xa Inhibitor
API Tulaga Maualuga, Gaosiga Fa'apisinisi
Igoa Vailaau | Fondaparinux Sodium |
Numera CAS | 114870-03-0 |
CAT Numera | RF-API84 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i le selau Kilograms |
Fuafua mole | C31H43N3O49S8.10Na |
Molecular Weight | 1728.08 |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e i le Pa'epa'e Pa'epa'e |
Su'ega / Su'esu'ega Metotia | 95.0%~103.0% (fa'amamago) |
Solubility | Solufua i le Suavai, 2.0M Sodium Chloride ma le 0.5M Sodium Hydroxide ma e le mafai ona solu ile Ethanol |
Fa'ailoga 13C-NMR | Resonances mo Fondaparinux Sodium e tatau ona matauina i le 58.2, 29.5, 60.5, 60.8, 68.9, 69.2, 69.6, 98.9, 100.4, 101.1, 102.4, 103.9, 176.7 ma le 176.7.Ole suiga ole vaila'au o nei faailo e le eseese ile sili atu i le ± 0.3ppm isi fa'ailoga ole maualuga fesuisuiai ma suiga ole vaila'au, e mafua mai i le Fondaparinux Sodium, atonu e va'aia i le va o le 58.0 ~ 80.5 ppm ma le 98.7 ~ 104.5ppm |
Fa'ailoga HPLC | Ole taimi fa'atumauina ole tumutumu tele ole fofo fa'ata'ita'i e fetaui ma le vaifofo masani |
Faailoaina AAS | O le sodium e tatau ona i ai uiga faʻafefe i le 330.2nm i lalo ole faʻamoemoega ole sodium |
pH | 6.0~8.0 |
Sodium (Na) | 11.5%~15.0% (Fa'atatau ile anhydrous ma solvents free) |
Saoloto Sulfate | ≤0.30% |
Chloride totoe | ≤1.00% |
Mea Fa'atatau | |
Le mama A | ≤0.80% |
Le mama B | ≤0.60% |
Nofofua Isi Le mama | ≤0.30% |
Aofa'i Fa'aleaga | ≤2.00% |
Solvents totoe | |
Methanol | ≤3000ppm |
Ethanol | ≤5000ppm |
Ethyl Acetate | ≤5000ppm |
DMF | ≤880ppm |
Methylbenzene | ≤890ppm |
Pyridine | ≤50ppm |
Suavai (KF) | ≤15.0% |
Endotoxins siama | ≤3.3EU/mg |
Tapulaa Microbial | Ole aofa'i ole Microorganisms ≤100cfu/g |
Tulaga Su'ega | Atina'e Atina'e;United States Pharmacopoeia (USP) Standard |
Fa'aoga | API, O le Antithrombotic Anticoagulant, o le Factor Xa Inhibitor |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
![1](https://www.ruifuchemical.com/uploads/15.jpg)
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Fondaparinux Sodium (CAS 114870-03-0) o le muamua lea o se vasega fou o le antithrombotic anticoagulant e fesoʻotaʻi ma le maualalo o le molecular weight heparins (LMWH).Fondaparinux sodium ose mea Xa inhibitor e fausia ai le nofoaga faʻamaufaʻatasiga maualuga mo le anti-coagulant factor antithrombin III (ATIII).O le fusifusia o le sodium Fondaparinux i lenei nofoaga e faʻamalosia ai le faʻalavelave faʻanatura o le ATIII e faasaga i le mea Xa e tusa ma le 300, lea e mafua ai le taofiofia o le gaosiga o le thrombin.O loʻo maketiina e GlaxoSmithKline.O se fa'ata'ita'iga lautele na fausia e Alchemia o lo'o fa'atauina i totonu ole US e Dr. Reddy's Laboratories.Fondaparinux sodium na muamua fa'aofiina i le US mo le puipuia o le loloto o le vein thrombosis lea e mafai ona o'o atu ai i le pulmonary embolism pe a mae'a le taotoga tele.O lenei mole mole faʻapipiʻi atoa o se kopi o le faʻasologa o le pentasaccharide heparin, o le vaega pito sili ona puʻupuʻu e mafai ona faʻapipiʻiina le antithrombin i le faʻaogaina o le faʻalavelave Xa ma faʻafefe ai le gaosiga o le thrombin e aunoa ma se gaioiga antithrombin.
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