Fulvestrant (ICI 182780) CAS 129453-61-8 API Falegaosi Mea Maualuluga

Fa'amatalaga Puupuu:

Igoa: Fulvestrant (ICI 182780)

CAS: 129453-61-8

Fa'aaliga: Pa'epa'e i le Pa'u Pa'epa'e Pa'epa'e

Su'ega: 97.0%~102.0% (fa'amamago)

O le Fulvestrant e fa'aaogaina i le togafitiga o le kanesa o le susu maualuga e ma'ale'ale i le homone i fafine ua mae'a le fa'ata'ita'iga.

API Tulaga Maualuga, Gaosiga Fa'apisinisi

Inquiry: alvin@ruifuchem.com

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Fa'amatalaga:

Tuuina atu a le Faumea ma le Mamalu Maualuga ma le Tulaga Lelei
Igoa: Fulvestrant
CAS: 129453-61-8
O le Fulvestrant e fa'aaogaina i le togafitiga o le kanesa o le susu maualuga e ma'ale'ale i le homone i fafine ua mae'a le fa'ata'ita'iga.
API Tulaga Maualuga, Gaosiga Fa'apisinisi

Meatotino tau vailaau:

Igoa Vailaau	Fulvestrant
Synonyms	(7α,17β)-7-[9-[(4,4,5,5,5-Pentafluorpentyl)sulfinyl]nonyl]estra-1,3,5(10)-trien-3,17-diol;ICI 182780
Numera CAS	129453-61-8
CAT Numera	RF-API81
Tulaga Fa'asoa	I Fa'atauga, Oloa Fua e O'o i le selau Kilograms
Fuafua mole	C32H47F5O3S
Molecular Weight	606.77
Lisi Lisi	104.0~106.0 ℃
Solubility	Solu i le Methanol, Ethanol;E le mafai ona solu i le Vai
Fa'ailoga	Ruifu Chemical

Fa'amatalaga:

Aitema	Fa'amatalaga
Fa'aaliga	Pa'epa'e i le Pa'u Pa'epa'e Pa'epa'e
Fa'ailoaga	Saunia e IR, HPLC
Fa'asinomaga Fa'ailo	+108.0° i le +115.0°
Ma'imau ile Fa'amago	≤0.50%
Toega i luga o le mumu	≤0.10%
6-Keto-Fulvestrant	≤0.10%
6,7-Fulvestrant	≤0.10%
Fulvestrant Sulfone	≤0.20%
Fulvestrant Extended	≤0.30%
Fulvestrant Sterol Dimmer	≤0.80%
So'o se Tagata Ta'ito'atasi Le Fa'amamafaina Fa'aleaga	≤0.10%
Aofa'i Fa'aleaga	≤1.0%
Fulvestrant A	42.0%~48.0%
Fulvestrant B	52.0%~58.0%
DMF	≤620ppm
Metala mamafa	≤10ppm
Su'ega	97.0%~102.0% (fa'amamago)
Teuga	Fa'asa'o i totonu o koneteina tapuni lelei ma fa'asa'o moli fa'a'aisa i le 2~8 ℃
Tulaga Su'ega	United States Pharmacopoeia (USP) Standard
Fa'aoga	Estrogen Receptor Antagonist

Paket & Teuina:

afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.

Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.

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Talosaga:

Fulvestrant (ICI-182780) CAS 129453-61-8, o se vailaʻau tui maso na atiaʻe e le kamupani AstraZeneca ma o loʻo faʻaaogaina i le togafitiga o le kanesa o le susu maualuga o le hormone-maʻaleʻale i fafine ua maeʻa le menopause.Fulvestrant e na'o le pau lea o vaila'au fa'ama'i e mafai ona fa'aoga lautele ile falema'i pe a mae'a togafitiga le manuia ole tamoxifen.O lenei vaila'au o se ituaiga o togafitiga o le endocrine, o lea o le a le mafua ai ni a'afiaga leaga e masani ona va'aia i le chemotherapy, e maua ai le tausisia lelei o le gasegase.Ole tele o su'esu'ega ile falema'i ua maua ai ole 250mg Fulvestrant e aoga ma saogalemu e fai ma laina lona lua ole togafitiga mo le kanesa o le susu.Fulvestrant ose Estrogen Receptor (ER) Antagonist faʻatasi ma IC50 o le 0.94 nM i se suʻega e leai se sela.Fulvestrant fa'aosoina fo'i le autophagy ma le apoptosis ma o lo'o iai ni gaioiga fa'atosina.