Guanfacine Hydrochloride Guanfacine HCl CAS 29110-48-3 API USP tulaga maualuga mama maualuga
Faumea e maualuga le mama ma mautu lelei
Igoa vaila'au: Guanfacine Hydrochloride
Synonyms: Guanfacine HCl
CAS: 29110-48-3
Guanfacine Hydrochloride o se α2A-adrenoceptor agonist filifilia.Fa'ateteleina
API Tulaga Maualuga, Gaosiga Fa'apisinisi
Igoa Vailaau | Guanfacine Hydrochloride |
Synonyms | Guanfacine HCl |
Numera CAS | 29110-48-3 |
CAT Numera | RF-API40 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C9H10Cl3N3O |
Molecular Weight | 282.55 |
Lisi Lisi | 211.0~215.0 ℃ |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e i le Pa'u Pa'epa'e Pa'epa'e |
Fa'ailoaga | Infrared absorption;HPLC |
Ma'imau ile Fa'amago | ≤0.50% |
Toega i luga o le mumu | ≤0.10% |
Metala mamafa | ≤20ppm |
Su'ega | 98.0%~102.0% (HPLC ile fa'amamago) |
Chromatographic mama | ≥99.0% |
Tulaga Su'ega | USP Standard |
Fa'aoga | Mea Fa'afoma'i Gaoioiga (API) |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua ma le tuʻuina atu o Guanfacine Hydrochloride (CAS: 29110-48-3) faʻatasi ai ma le maualuga.
Guanfacine hydrochloride o loʻo galue i totonu ole a-adrenoceptor agonist.Fa'ateteleina.Guanfacine hydrochloride, o le anti-hypertensive agent, o se α2A-adrenoceptor agonist filifilia ma Kd o le 31 nM ma faʻaalia le 60-fold selectivity i luga ole α2B-adrenoceptors.Guanfacine e faʻaititia uma le toto systolic ma le diastolic e ala i le faʻagaoioia o le fatugalemu o le neura o le α2A norepinephrine autoreceptors, lea e mafua ai le faʻaitiitia o le faʻafefe alofa i fafo ma faʻaitiitia ai le leo alofa alofa.O fa'ata'ita'iga mo le guanfacine e tutusa lelei ma isi fa'atonuga o le α2-adrenergic agonists ma le methyldopa.Ua aoga e pei o le monotherapy i le togafitiga o tagata mama'i i le maualuga maualuga.