H-Gly-OMe·HCl CAS 5680-79-5 Glycine Methyl Ester Hydrochloride Su'ega >99.0%

1. Meatotino: O lenei oloa e tatau ona paʻepaʻe tioata tioata.
2. Su'ega:
1) Fuafuaga ole Glycine Methyl Ester Hydrochloride suʻega
1.1 Metotia
I lalo o tulaga oona, o le faʻataʻitaʻiga e tali atu i se aofaʻi o le silver nitrate, ma o le sili atu o le silver nitrate e toe faʻafoʻi i le ammonium thiocyanate, e faʻatatau i le ammonium ferric sulfate.
I le avea ai ma faʻailoga, o le aofaʻi o le chlorine na faʻamoemoeina e tusa ai ma le tele o le vaifofo masani na faʻaaogaina, ma o le aofaʻi o le chlorine na toesea mai le anotusi o le glycine hydrochloride e maua ai le Glycine Methyl Ester Hydrochloride content.
1.2 Reagents
Dibutyl phthalate;
Nitric acid solution: 2+3;
Silver nitrate vaifofo titration masani: c(AgNO3) = 0.1 mol/L
Ammonium thiocyanate fofo titration masani: c(NH4SCN) = 0.1 mol/L
Ammonium ferric sulfate (III) fa'ailo vai: 80 g/L
1.3 Fa'asologa o Su'esu'ega
Fua e tusa ma le 0.5g fa'ata'ita'iga, sa'o i le 0.0001g.Tu'u i totonu o se fagu conical 250ml, solo i le 40ml vai, fa'aopopo 10 ml nitric acid solution, Fa'aopoopo (50 ± 0.02) mL silver nitrate solution titration standard, 3mL ammonium ferric sulfate indicator solution, 4mL dibutyl phthalate, ma le thiocyanate Ammonium solution titration standard. titrated seia oo ina lanu enaena le vai ma tumau pea le lanu mo le 30 s.
1.4 Fa'ai'uga fa'atatau
Ole vaega tele ole glycine methyl ester hydrochloric acid content w1, o lo'o fa'aalia i le%, ua fa'atatau ile Fa'atusa (1):
w1= (c1V1-c2V2)*M/1000/m * 100-w2 *1.126 fua (1)
O fea:
V1: Volula ole vaifofo fua fa'avasegaina ole nitrate siliva (ml)
V2: Volomao o le ammonium thiocyanate vaifofo fua fa'atatau o lo'o fa'aaogaina e ala i le titration (ml)
c1: Tau sa'o ole vaifofo titration masani ole nitrate siliva (mol/L)
c2: Tau sa'o o le ammonium thiocyanate vaifofo titration masani (mol/L)
w2: Fa'asao vaega (%) o le glycine hydrochloride anotusi e pei ona fuafuaina i le Vaega 4.2
M: Molar mass o le glycine methyl ester hydrochloride (g/mol)
1.126: Fa'aliliuga o le glycine hydrochloride i le Glycine methyl ester hydrochloride.
O le fua fa'atatau o fua fa'atatau e lua na avea ma fua fa'atatau, ma o le eseesega atoatoa i le va o fa'ai'uga tutusa e lua e le sili atu i le 0.05%.
2) Fuafuaga ole glycine hydrochloride anotusi
2.1 Metotia
I le faʻaaogaina o le dimethyl samasama e fai ma faʻailoga, o le faʻataʻitaʻiga na faʻapipiʻiina i le sodium hydroxide standard titrating solution, ma o le voluma o le vaifofo na titrated e tusa ai ma le taumafaina o le sodium hydroxide standard.
Fa'atatau le glycine hydrochloride i totonu.
2.2 Reagent
Ole vaifofo masani ole titration ole sodium hydroxide: c (NaOH) = 0.1mol/L
Dimethyl samasama fa'ailoga vai: 10 g/L
2.3 Fa'asologa o Su'esu'ega
Fua pe tusa ma le 5.0 g fa'ata'ita'iga su'esu'e, sa'o i le 0.0001g, i totonu o se fagu 200 ml, fa'amuta i le vai 50ml, ma fa'aopopo i ai le 5 mataua o le dimethyl.
Suavai fa'ailoga samasama, fa'atasi ai ma le sodium hydroxide standard titration solution titration se'ia o'o le vaifofo mai le mumu i le moli samasama o le fa'ai'uga.
2.4 Fa'ai'uga Fa'atatau
Ole vaega w2 ole glycine hydrochloride anotusi o lo'o fa'aalia ile% ma fa'atatau ile Fa'atusa (2):
w2 =(V/1000)cM/m *100 fua (2)
O fea:
V: Volume o le sodium hydroxide vaifofo fua fa'atatau (mL)
c: Sa'o sa'o o le sodium hydroxide fua fa'atatau o vaifofo fa'avasega (mol/L)
M: Molar mass o le glycine hydrochloride (g/mol)
m: Taua tele o le fa'ata'ita'iga (g)
O le fua fa'atatau o fua fa'atatau e lua na ave e fai ma fua fa'atatau, ma o le 'ese'ese atoatoa i le va o fa'ai'uga tutusa e lua e le sili atu i le 0.05%
3. Mea e liusuavai ai: E tusa ai ma le metotia o le su'esu'eina o le mea e fa'afefeteina ai (Chinese Pharmacopoeia 2010 Appendix VIC), o le vaega fa'afefeteina o le 172-178 ºC.
4. Fa'amamago pa'u mamafa: ave lenei oloa i le 105.0 ℃ ma fa'agogo i le mamafa tumau.Ole pa'u mamafa e le tatau ona sili atu ile 0.5%.
5. Teuina: O lenei oloa e tatau ona faʻafefete ese mai le malamalama.