Ibrutinib Deacryloylpiperidine CAS 330786-24-8 Mama >99.0% (HPLC)
Igoa Vailaau | 3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Synonyms | Ibrutinib intermeidate N-2;Ibrutinib Deacryloylpiperidine;Ibrutinib Le mama 8;5-(4-Phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine;IBT4A;Ibrutinib N-Despiperidinyl Le mama |
Numera CAS | 330786-24-8 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C17H13N5O |
Molecular Weight | 303.32 |
Lisi Lisi | >262℃(Tes.) |
Malosi | 1.380±0.06 g/cm3 |
Vasega o Tulaga Lamatia | 6.1;Oona |
Fa'aputuga Vaega | III |
COA & MSDS | Avanoa |
Amataga | Shanghai, Saina |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e-Pa'epa'e i le Pa'u Khaki |
Fa'ailoaga | HNMR, LC-MS |
Mama / Suʻesuʻega Metotia | >99.0% (HPLC) |
Ma'imau ile Fa'amago | <1.00% |
Nofofua Max.le mama | <1.00% |
Aofa'i Fa'aleaga | <1.00% |
Metala mamafa (pei o le Pb) | <20ppm |
Tulaga Su'ega | Enterprise Standard |
Fa'aoga | Intermediate of Ibrutinib (CAS: 936563-96-1) |
afifi: Fagu, taga pepa alumini, 25kg / Cardboard Drum, pe tusa ai ma manaoga o tagata faatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu.
3-(4-Phenoxyphenyl) -1H-pyrazolo [3,4-d] pyrimidin-4-amine (CAS: 330786-24-8) o se mea faʻaoga faʻapipiʻi aoga i le tuʻufaʻatasia o Ibrutinib (CAS: 936563-96-1 ).Ibrutinib o se ituaiga o Bruton tyrosine kinase (BTK) inhibitor, e mafai ona faʻaaogaina mo le togafitia o le leukemia lymphocytic masani (CLL) ma le lymphoma sela (MCL).O le MCL ma le CLL e a'afia i le B-cell non-Hodgkin's lymphoma, lea e faigata ona fofo ma faigofie ona toe tupu.Ole fa'ama'i fa'ama'i masani e leai se fa'atatau, e masani ona tupu ile 3 pe 4 fa'alavelave leaga.Ibrutinib ma B lymphocytes e mafai ona taulaʻi i le BTK lea e manaʻomia mo le faʻavaeina, faʻavasegaina, ma le tuʻuina atu o faʻamatalaga, faʻalavelaveina le gaioiga o le BTK e le mafai ona toe faʻafoʻisia, ma faʻalavelaveina le tuputupu aʻe o le tumo ma le ola lelei.Ibrutinib e mafai ona vave faʻafefe pe a uma le tautala tautala, i le taimi o le 1 ~ 2h e oʻo atu i le maualuga o le toto maualuga, o aʻafiaga leaga e tasi pe lua, o le mea lea, o le a avea Ibrutinib ma se filifiliga fou o togafitiga o CLL ma MCL.