Irbesartan CAS 138402-11-6 Mama>99.0% (HPLC) API Falegaosi Mea e fa'agata ai le toto maualuga.
Manufacturer Sapalai, Mama maualuga, Gaosiga Faapisinisi
| Igoa Vailaau | Irbesartan |
| Synonyms | BMS-186295;SR-47436;Aprovel;Avapro;2-Butyl-3-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en- 4-tasi;2-Butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]e le-1-en-4-one |
| Numera CAS | 138402-11-6 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
| Fuafua mole | C25H28N6O |
| Molecular Weight | 428.54 |
| Malosi | 1.30±0.10g/cm3 |
| Solubility i le Vai | E le mafai ona solu i le Vai |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Uiga | Pa'epa'e i le Pa'epa'e Pa'epa'e Pa'epa'e, E so'a teisi i le ava malosi ma le methylene chloride, toetoe lava a le mafai ona so'u ile vai. |
| Faailoaina Infrared Absorption | Ole fusi ole IR e tusa ai ma le fusi ole alaleo na maua ile Irbesartan RS |
| Faailoaina 2 | Ole taimi ole taofi ole pito maualuga ile chromatogram ole suʻega e fetaui ma Irbesartan RS |
| Mama / Suʻesuʻega Metotia | >99.5% (HPLC) |
| Vai | <0.50% |
| Metala mamafa | <0.002% |
| Toega i luga o le mumu | <0.10% |
| Mea Fa'atatau | (Saunia e HPLC) |
| USP Le mama A | <0.20% |
| So'o se mea e le fa'amamafaina | <0.10% |
| Aofa'i Fa'aleaga | <0.50% |
| Organic VolatileImpurities | Faʻafeiloaʻi manaʻoga a le USP |
| Azide totoe | <10ppm |
| Solvents totoe | (Saunia e GC) |
| Ethanol | <5000ppm |
| Toluene | <890ppm |
| Dichloromethane | <3000ppm |
| N,N-Dimethylformamide | <880ppm |
| T-Butyl Methyl Eteru | <5000ppm |
| Su'ega | 98.0~102.0% (fa'atatau i luga ole fa'avae) |
| Tulaga Su'ega | Atina'e Atina'e;USP Standard |
| Fa'aoga | API;Fa'ateteina le toto;Mo togafitiga o le toto maualuga |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
Irbesartan (CAS: C) o le angiotensin II receptor antagonist faʻaaogaina mo togafitiga o le toto maualuga.Irbesartan na fausia e le Sanofi Research (lea ua avea nei ma vaega o Sanofi-Aventis).O loʻo faʻatau faʻatasi e Sanofi-Aventis ma Bristol-Myers Squibb i lalo o igoa tau fefaʻatauaʻiga Aprovel, Karvea, ma Avapro.Irbesartan e faʻaaogaina e togafitia ai le toto maualuga.Avapro na faʻalauiloaina i Siamani, Peretania ma le US mo le toto maualuga.E pei o le angiotensin II antagonists uma, o le irbesartan o loʻo faʻaalia mo togafitiga o le toto maualuga.E mafai foʻi e Irbesartan ona faʻatuai le alualu i luma o le nephropathy o le maʻisuka ma o loʻo faʻaalia foi mo le faʻaitiitia o le alualu i luma o faʻamaʻi fatugaʻo i tagata mamaʻi e maua i le maʻisuka ituaiga 2, toto maualuga ma microalbuminuria (> 30 mg / 24 itula) poʻo le proteinuria.E mafai foi e Irbesartan ona faʻaitiitia le toe faʻaleleia o le eletise o le myocardium, ma faʻaitiitia ai le numera o tagata gasegase e maua i le toto maualuga, o le vailaʻau sili ona aoga mo togafitiga o le toto maualuga ma le maʻi cardiovascular.
