L-Alaninamide Hydrochloride CAS 33208-99-0 (H-Ala-NH2·HCl) Su'ega 98.0~102.0% Safinamide Intermediate Factory
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua ma le tuʻuina atu o le L-Alaninamide Hydrochloride (H-Ala-NH2·HCl) (CAS: 33208-99-0) faʻatasi ai ma le maualuga, o se vaeluaga o Safinamide (CAS: 133865- 89-1).E mafai ona matou tuʻuina atu i le lalolagi atoa le tuʻuina atu, laʻititi ma tele aofaʻi avanoa.Afai e te manaʻomia L-Alaninamide Hydrochloride,Please contact: alvin@ruifuchem.com
| Igoa Vailaau | L-Alaninamide Hydrochloride |
| Synonyms | L-Alaninamide HCl;H-Ala-NH2·HCl;L-Ala-NH2·HCl;(S)-2-Aminopropionamide Hydrochloride;(S)-2-Aminopropionamide HCl;(2S)-2-Aminopropanamide Hydrochloride |
| Tulaga Fa'asoa | I Fa'atauga, Gaosi Gaosi 100 Tone i le Tausaga |
| Numera CAS | 33208-99-0 |
| Fuafua mole | C3H8N2O·HCl |
| Molecular Weight | 124.57 g/mol |
| Lisi Lisi | 200.0~220.0 ℃ |
| Ma'ale'ale | Ea maaleale |
| Solubility | Solu i le Methanol |
| Temp. | Faamaufa'ailoga i le mago, teu i le vevela o le potu |
| COA & MSDS | Avanoa |
| Fa'avasegaga | Amino Acids & Derivatives |
| Fa'ailoga | Ruifu Chemical |
| Laiti o lamatiaga | C - A'a | WGK Siamani | 3 |
| Fa'amatalaga Saogalemu | 24/25 - Aloese mai le fa'afeso'ota'i ma le pa'u ma mata. | HS Code | 2922491990 |
| Aitema | Tulaga Fa'atonu | I'uga |
| Fa'aaliga | Pa'epa'e i le Pa'epa'e Pa'epa'e | Fa'atatau |
| Infrared Spectrometry | E tusa ma le Fauga | Fa'atatau |
| Su'ega / Su'esu'ega Metotia | 98.0~102.0% | 99.3% |
| Lisi Lisi | 200.0~220.0 ℃ | 214.0~216.0 ℃ |
| Ta'amilosaga Fa'apitoa [α]20/D | +9.0° i le +13.0°(C=1, CH3OH) | +12.43° |
| Ma'imau ile Fa'amago | <0.50% | 0.15% |
| Toega i luga o le mumu | <0.10% | 0.05% |
| Uamea (Fe) | <10ppm | <10ppm |
| Sulfate (SO4) | <0.02% | <0.02% |
| Metala mamafa (Pb) | <10ppm | <10ppm |
| Ammonium (NH4) | <0.08% | <0.08% |
| Arsenic (As2O3) | <1ppm | <1ppm |
| Fa'ai'uga | Lenei Oloa e ala ile Asiasiga E tusa ai ma le Enterprise Standard | |
| Fa'aoga Autu | Vailaau Fa'atekonolosi;Safinamide Intermediate | |
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Fa'afefea ona Fa'atau?Fa'amolemole fa'afeso'ota'iDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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L-Alaninamide Hydrochloride (H-Ala-NH2·HCl) (CAS: 33208-99-0) o loʻo faʻaaogaina e avea ma vailaʻau faʻapitoa.L-Alaninamide Hydrochloride o loʻo faʻaaogaina mo le saunia o tala fou amide derivatives o steroidal [3,2-c] pyrazole faʻatasi ma le gaioiga glucocorticoid.L-Alaninamide Hydrochloride o se vaeluaga o Safinamide (CAS: 133865-89-1) ma Safinamide Mesylate (CAS: 202825-46-5).O le Safinamide o se fa'ailo filifilia ma fa'aliliuina o le monoamine oxidase B (MAO-B, IC50 = 98 nM fa'atasi ai ma le sili atu i le 100-fold selectivity i luga o le MAO-A. Fa'aalia le gaioiga fa'aanticonvulsant ma puipuia mai le faoa faoa o le kainate ma le neurodegeneration hippocampal i fa'ata'ita'iga iole. Fa'aitiitia fa'ailoga o le glutamatergic le malosi e ala i le fa'aogaina o le fa'aogaina o le sodium channel blockade. O se togafiti fou mo le ma'i o Parkinson ma le tele o auala o gaioiga. E aoga e fai ma fa'aopoopoga i le dopamine agonist therapy i le amataga o Parkinson. Safinamide methanesulfonate na fa'atagaina ia Fepuari 2015 e le EMA mo togafitiga. o le vaeluagalemu i le tuai-tulaga faʻasolosolo faʻamaʻi o Parkinson.O lenei faʻatagaga na aofia ai le faʻaaogaina o vailaʻau e fai ma togafitiga faʻaopoopo mo le faʻaogaina ma Levodopa, pe naʻo ia pe faʻatasi ma isi togafitiga o loʻo iai mo le maʻi o Parkinson Safinamide methanesulfonate, o le oral α-aminoamide na maua muamua e Farmitalia Carlo Erba ma mulimuli ane atiina ae e Newron/Zambon, galue o se inhibitor sili ona filifilia ma toe faʻafoʻisia o le MAO-B, e taʻitaʻia ai le maualuga o le dopamine ma faʻaleleia mulimuli ane i faʻamaʻi afi o le maʻi o Parkinson, aʻafiaga e masani ona tupu mai. fa'aogaina o isi togafitiga fa'aleaganu'u e fa'alagolago i togafitiga e sui ai le dopamine.
