Lasofoxifene Tartrate CAS 190791-29-8 Chiral Mama ≥99.0% Mama ≥98.0% (HPLC) API Mama maualuga
Tuuina atu a le Faumea ma le Mamalu Maualuga ma le Tulaga Lelei
Igoa vaila'au: Lasofoxifene Tartrate
CAS: 190791-29-8
Lasofoxifene Tartrate (CAS: 190791-29-8) ile togafitiga ole Postmenopausal Osteoporosis
Igoa Vailaau | Lasofoxifene Tartrate |
Synonyms | (5R,6S)-5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol Tartrate Oporia |
Numera CAS | 190791-29-8 |
CAT Numera | RF-API20 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i le selau Kilograms |
Fuafua mole | C28H31NO2.ClH |
Molecular Weight | 450.019 |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e i le Pa'epa'e Pa'epa'e |
Susū (KF) | ≤0.50% |
Metala mamafa | ≤20ppm |
Chiral Mama | ≥99.0% |
Mama / Suʻesuʻega Metotia | ≥98.0% (HPLC) |
Ma'imau ile Fa'amago | ≤0.50% |
Toega i luga o le mumu | ≤0.50% |
Tulaga Su'ega | Pharmacopoeia Saina (CP);Pisinisi Tulaga |
Fa'aoga | Gaoioiga Fa'afoma'i Mea'ai (API);Osteoporosis pe a uma le manava |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua ma tuʻuina atu le Lasofoxifene Tartrate (CAS: 190791-29-8) faʻatasi ai ma le maualuga.
Lasofoxifene Tartrate o se tupulaga lona tolu, non-steroidal selective estrogen receptor modulator (SERM).E fusifusia faʻatasi i le tagata ERalpha ma le IC50 tau o le 1.5 nM ma faʻalavelaveina le gau o ponaivi i isumu ovariectomized.I suʻesuʻega faʻafomaʻi o le osteoporosis postmenopausal, 0.5 mg / aso lasofoxifene na fesoʻotaʻi ma le faʻaitiitia o aʻafiaga o le gau o le vertebral ma le vertebral, ER-positive kanesa o le susu, fatu fatu fatu, ma le taʻavale ae o le faʻateleina o aʻafiaga o mea e tutupu i le thromboembolic vena.O le Lasofoxifene ua faʻaalia foi e galue o se agonist faʻafefe i le CB2 cannabinoid receptor, e faʻaalia ai lona gafatia e toe faʻaaogaina e avea o se togafitiga mo faʻamaoniga o le CB2 o se taulaʻiga.