Lenvatinib Mesylate Intermediate CAS 205448-65-3 Mama >98.0% (HPLC) Fa'aaliga Fa'apitoa o Fale

Lenvatinib Mesylate Intermediate CAS 205448-65-3 Mama>98.0% (HPLC) Falegaosimea

Fa'amatalaga Puupuu:

Igoa Vailaau: Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate

CAS: 205448-65-3

Mama: >98.0% (HPLC)

Fa'aaliga: Pa'epa'e-Pa'epa'e ile Pa'u Samasama

Intermediate o Lenvatinib Mesylate CAS 857890-39-2

E-Mail: alvin@ruifuchem.com

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Fa'amatalaga:

Ruifu Chemical Supply Lenvatinib Mesylate Intermediates ma maualuga mama
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Meatotino tau vailaau:

Igoa Vailaau	Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate
Synonyms	1,4-Dihydro-7-Methoxy-4-Oxo-6-Quinolinecarboxylic Acid Methyl Ester;7-Methoxy-4-Oxo-1,4-Dihydro-Quinoline-6-Carboxylic Acid Methyl Ester;Lenvatinib Intermediate 3
Numera CAS	205448-65-3
CAT Numera	RF-PI1973
Tulaga Fa'asoa	I Fa'atauga, Gaosi Gaosi 50 MT/Tausaga
Fuafua mole	C12H11NO4
Molecular Weight	233.22
Fa'apuna	421.0±45.0℃
Malosi	1.267±0.060g/cm3
Fa'ailoga	Ruifu Chemical

Fa'amatalaga:

Aitema	Fa'amatalaga
Fa'aaliga	Pa'epa'e-Pa'epa'e i le Pa'u Samasama
Mama / Suʻesuʻega Metotia	>98.0% (HPLC)
Ma'imau ile Fa'amago	<1.00%
Toega i luga o le mumu	<0.50%
Aofa'i Fa'aleaga	<2.00%
H-NMR	E tusa ai ma le Fauga
Tulaga Su'ega	Pisinisi Tulaga
Fa'aoga	Vailaau Fa'atekonolosi

Paket & Teuina:

afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau

Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu

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Talosaga:

Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate (CAS: 205448-65-3) o se vaeluaga ole Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib, fa'atau atu i lalo o le igoa Lenvima fa'atasi ai ma isi, o se vaila'au e puipuia ai le kanesa mo le togafitia o nisi ituaiga o kanesa thyroid ma mo isi kanesa.Na atiina ae e Eisai Co. ma galue o se iniseti kinase tele e faasaga i le VEGFR1, VEGFR2 ma VEGFR3 kinases.Lenvatinib ua faʻatagaina (talu mai le 2015) mo le togafitiga o le kanesa thyroid eseese lea e le masani ai i le lotoifale poʻo metastatic, alualu i luma, ma e leʻi tali atu i togafitiga i le iodine radioactive (radioiodine).I le masina o Me 2016, na faʻamaonia ai e le US Food and Drug Administration (FDA) (faʻatasi ma le everolimus) mo le togafitiga o le gasegase o le tino o le tino pe a maeʻa le togafitiga muamua o le anti-angiogenic.O le vailaʻau e faʻamaonia foi i le US ma i le Europa Europa mo le hepatocellular carcinoma e le mafai ona aveese faʻamaʻi i tagata mamaʻi e leʻi mauaina togafitiga o le kanesa i le gutu poʻo le tui.