Linagliptin CAS 668270-12-0 Mama ≥99.0% (HPLC) Falegaosimea
Manufacturer Sapalai, Mama maualuga, Gaosiga Faapisinisi
Igoa vaila'au: Linagliptin
CAS: 668270-12-0
Igoa Vailaau | Linagliptin |
Synonyms | BI-1356;8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butynyl) -3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H -purine-2,6-dione |
Numera CAS | 668270-12-0 |
CAT Numera | RF-API105 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C25H28N8O2 |
Molecular Weight | 472.54 |
Lisi Lisi | 197.0 i le 200.0 ℃ |
Solubility | Solu i le DMSO |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'u Pa'epa'e po'o le Pa'epa'e Pa'epa'e |
NMR | Osi ma le Fauga |
Mama / Suʻesuʻega Metotia | ≥99.0% (HPLC) |
Ma'imau ile Fa'amago | ≤0.50% |
Toega i luga o le mumu | ≤0.10% |
Metala mamafa | ≤10ppm |
Mea Fa'atatau | |
Le mama nofofua | ≤0.50% |
Aofa'i Fa'aleaga | ≤1.0% |
Isomer | ≤0.15% |
Solvents totoe | |
Methanol | ≤3000ppm |
Isopropanol | ≤5000ppm |
DMF | ≤800ppm |
Dichloromethane | ≤600ppm |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | API |
afifi: Fagu, Ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu.
Linagliptin (CAS: 668270-12-0) o le DPP-4 inhibitor na fausia e Boehringer Ingelheim mo togafitiga o le maʻisuka ituaiga II.E lua uiga faʻafomaʻi e tuʻu ese ai le linagliptin mai isi inhibitors DPP-4 o loʻo i ai se faʻamatalaga pharmacokinetic e le laina laina ma e leʻo faʻaumatia muamua e le tino.Linagliptin (tasi i aso uma) na faʻamaonia e le US FDA i le aso 2 Me 2011 mo togafitiga o le maʻisuka ituaiga II.O loʻo faʻatauina e Boehringer Ingelheim ma Lilly.Linagliptin, faʻatau atu i lalo o le igoa Tradjenta faʻatasi ma isi.E fa'aaogaina fa'atasi ma fa'amalositino ma mea'ai.