Methyl 2-Oxoindoline-6-Carboxylate CAS 14192-26-8 Mama >99.0% (HPLC) Nintedanib Esylate Intermediate Factory
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua ma le tuʻuina atu o Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) faʻatasi ai ma le maualuga, gaosiga faʻapisinisi.
Igoa Vailaau | Methyl 2-Oxoindoline-6-Carboxylate |
Synonyms | 2-Oxoindoline-6-Carboxylic Acid Methyl Ester;Methyl Oxindole-6-Carboxylate |
Numera CAS | 14192-26-8 |
CAT Numera | RF-PI1524 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C10H9NO3 |
Molecular Weight | 191.19 |
Lisi Lisi | 184.0~190.0 ℃ |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Samasama Malamalama i le Pata Enaena |
1 H NMR Alaleo | O gatasi ma le Fauga |
Mama / Suʻesuʻega Metotia | >99.0% (HPLC) |
Ma'imau ile Fa'amago | <1.00% |
Aofa'i Fa'aleaga | <1.00% |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | Intermediate of Nintedanib Esylate (CAS: 656247-18-6) |
Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) Auala fa'akomepiuta
afifi: Fagu, taga pepa alumini, 25kg / Cardboard Drum, pe tusa ai ma manaoga o tagata faatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu.
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Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) o se vaeluaga e faʻaaogaina e saunia ai le Nintedanib Esylate (CAS: 656247-18-6).O le Nintedanib Esylate o se mea malosi, oral triple angiokinase inhibitor na atiina ae e Boehringer Ingelheim lea e taulaʻi i auala proangiogenic ma pro-fibrotic e faʻatalanoaina e le vascular endothelial growth factor receptor, fibroblast growth factor receptor ma plateletderived growth factor receptors aiga, faʻapea foʻi ma Src ma Flt-3 kinase.Nintedanib Esylate na faʻamaonia mo togafitiga o le idiopathic pulmonary fibrosis (IPF), o se tulaga e faʻasolosolo ai le maʻila o mama i le aluga o taimi, e le US FDA ia Oketopa 2014 ma le EMA ia Ianuari 2015. Na tuʻuina atu e le FDA le nintedanib esylate fast-track. , iloiloga fa'amuamua, oloa matuaoti, ma fa'ailoga iloga.Na fa'amaonia fo'i e le EMA ia Novema 2014 mo le togafitia o le kanesa o le mama sela e le o ni sela laiti fa'atasi ma le docetaxel pe a mae'a le chemotherapy.
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