Molnupiravir N-1 CAS 2346620-55-9 COVID-19 Tulaga Maualuga
Sapalai Fefa'ataua'iga Molnupiravir ma Feso'ota'i Fesoota'i ma Tulaga Maualuga
Uridine CAS 58-96-8
Cytidine CAS 65-46-3
Molnupiravir N-1 CAS 2346620-55-9
Molnupiravir (EIDD-2801) CAS 2349386-89-4
| Igoa Vailaau | Molnupiravir N-1 |
| Synonyms | ((3aR,4R,6R,6aR)-6-((E)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3, 4-d][1,3]dioxol-4-yl)methyl isobutyrate;Molnupiravir Intermediate;Molnupiravir Dimethyl Dioxol Le mama;Molnupiravir Le mama 11 |
| Numera CAS | 2346620-55-9 |
| CAT Numera | RF-PI310 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i le selau Kilograms |
| Fuafua mole | C16H23N3O7 |
| Molecular Weight | 369.37 |
| Solubility | Solu i le DMSO |
| Malosi | 1.51±0.1g/cm3 |
| Va'a vevela | Ambient |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pa'epa'e i le Pa'epa'e Pa'epa'e |
| Ma'imau ile Fa'amago | ≤1.0% |
| Toega i luga o le mumu | ≤0.20% |
| Le mama nofofua | ≤0.50% |
| Aofa'i Fa'aleaga | ≤2.0% |
| Metala mamafa | ≤20ppm |
| Mama | ≥98.0% |
| Tulaga Su'ega | Pisinisi Tulaga |
| Fa'aoga | Vaitaimi ole Molnupiravir (CAS 2349386-89-4) COVID-19 |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
Molnupiravir N-1 (CAS 2346620-55-9), o le ogatotonu ole Molnupiravir (CAS 2349386-89-4) ile togafitiga ole COVID-19.O le Molnupiravir (EIDD-2801) o se fa'afofoga fa'afofoga fa'afofoga o se analog ribonucleoside malosi tele e taofia ai le toe faia o le tele o fa'ama'i RNA e aofia ai le SARS-CoV-2, le so'o fa'atupu o le COVID-19.EIDD-2801 (7 mg/kg; po; faalua i aso taitasi mo le 3.5 aso) e matua fa'aitiitia ai le mamafa o siama ma le umi o le fiva.Molnupiravir (EIDD-2801) e faʻaleleia lelei ile vivo pe a maeʻa le faʻaogaina, ma maua ai naʻo le NHC saoloto ile plasma.EIDD-2801 fa'aitiitia fa'aitiitiga fa'ama'i pipisi MERS-CoV, viral RNA, ma fa'ama'i fa'ama'i i lalo o tulaga e lua e puipuia ai ma vave togafitiga.O le Molnupiravir (EIDD-2801, MK-4482) o se vailaʻau faʻaola e mafai ona tuʻu tautala o le ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931) faʻatasi ai ma le lautele o alaleo antiviral gaioiga e faasaga i le SARS-CoV-2, MERS-CoV, SARS-CoV, ma le so'o fa'atupu ole COVID-19.
