N-Acetyl-L-Cysteine CAS 616-91-1 (Ac-Cys-OH; NAC) Su'ega 98.5~101.0% Falegaosimea Maualuluga
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua ma faʻatau atu le N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) faʻatasi ai ma le maualuga.Ruifu Chemical o lo'o tu'uina atu se fa'asologa o amino acids ma mea e maua mai ai.Ona o lo tatou tulaga lelei oloa, tau talafeagai, tatou maua le igoa lelei faapea foi ma le faatuatuaina mai o tatou tagata faatau i le fale ma fafo.E mafai ona matou tuʻuina atu COA, faʻasalalauga i le lalolagi atoa, laʻititi ma le tele o loʻo avanoa.Afai e te fiafia ile N-Acetyl-L-Cysteine,Please contact: alvin@ruifuchem.com
Igoa Vailaau | N-Acetyl-L-Cysteine |
Synonyms | Ac-Cys-OH;Acetylcysteine;NAC;LNAC;N-Acetylcysteine;N-Acetyl-3-Mercaptoalanine;Acetyl-Laevo-Cysteine |
Tulaga Fa'asoa | I Fa'atauga, Gaosi Gaosi 50 Tone i le Masina |
Numera CAS | 616-91-1 |
Fuafua mole | C5H9NO3S |
Molecular Weight | 163.19 |
Lisi Lisi | 106.0~108.0 ℃(malamalama) |
Ma'ale'ale | Ea maaleale |
Suavai Solubility | Solu i le Suavai, Toeititi lava manino |
Solubility | Solu i le Ethanol, Methanol, Alcohol.E le mafai ona solu i le Eteru |
Temp. | Faamaufa'ailoga i le mago, teu i le vevela o le potu |
COA & MSDS | Avanoa |
Fa'avasegaga | Amino Acids & Derivatives |
Fa'ailoga | Ruifu Chemical |
Fa'amatalaga Tulaga lamatia | 36/37/38 - Fa'aitaita'i i mata, faiga fa'alenava ma le pa'u. |
Fa'amatalaga Saogalemu | S22 - Aua le manava pefu.S24/25 - Aloese mai le pa'i i le pa'u ma mata. |
WGK Siamani | 3 |
RTECS | HA1660000 |
F | 10-23 |
TSCA | Ioe |
HS Code | 2922491990 |
Aitema | Tulaga Fa'atonu | I'uga |
Fa'aaliga | Maila Pa'epa'e po'o le Pa'u Fa'ameamea;Malosi Acid Tofo | Fa'atatau |
Fa'ailoaga | Fusi Alaleo Fa'a'aalaula | Fa'atatau |
Ta'amilosaga Fa'apitoa [α]20/D | +21.3° i le +27.0° (C=5 ile Phosphate Buffered Saline) | +23.5° |
Tulaga o Fofo (Transmittance) | manino ma le lanu ≥98.0% | 99.0% |
Klorida (Cl) | ≤0.040% | <0.040% |
Sulfate (SO4) | ≤0.030% | <0.030% |
Ammonium (NH4) | ≤0.020% | <0.020% |
Uamea (Fe) | ≤20ppm | <20ppm |
Metala mamafa (Pb) | ≤10ppm | <10ppm |
Zinc (Zn) | ≤10ppm | <10ppm |
Arsenic (As2O3) | ≤1.0ppm | <1.0ppm |
Mea Fa'atatau | (Metotia HPLC) | |
L-Cystine | ≤0.50% | Fa'atatau |
L-Cysteine | ≤0.50% | Fa'atatau |
N,N'-Diacetyl-L-Cystine | ≤0.50% | Fa'atatau |
N,S-Diacetyl-L-Cysteine | ≤0.50% | Fa'atatau |
Le tasi ma le isi Le mama | ≤0.50% | Fa'atatau |
Aofa'i Fa'aleaga | ≤0.50% | Fa'atatau |
Ma'imau ile Fa'amago | ≤0.50% | 0.20% |
Toega ile mumu (Sulfated) | ≤0.20% | 0.05% |
Su'ega | 98.5 i le 101.0% (i luga ole Fa'amamago) | 99.90% |
pH Taua | 2.0 i le 2.8 (1.0g i le 100ml H2O) | 2.5 |
Oona oona | Pasi | Pasi |
Mea Fa'aletino Volatile | Pasia | Pasia |
Endonuclease Su'esu'ega | ≤0.1 EU/g | <0.1 EU/g |
Fa'ai'uga | Lenei oloa e ala ile asiasiga e tusa ai ma le tulaga o le AJI97 | |
Fa'aoga Autu | Amino acids;Mea'ai faaopoopo;Vailaau Fa'atekonolosi |
N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) Metotia Suʻega AJI97
N-Acetyl-L-Cysteine, pe a faʻamago, e le itiiti ifo i le 98.5 pasene ma e le sili atu ile 101.0 pasene ole N-Acetyl-L-Cysteine (C5H9NO3S).
Fa'amatalaga: O tioata pa'epa'e po'o le pa'u tioata, malosi le tofo oona.
Solufua i le vai, solu i le ethanol, toetoe a le mafai ona solu i le eter.
Solubility (H2O, g/100g): 17 (20℃), 80 (40℃), 260 (60℃)
Fa'ailoaina: Fa'atusatusa le fusi o le fa'ata'ita'i fa'ata'ita'i fa'atasi ma le fa'ata'ita'iga e ala i le metotia tisiketi o le potassium bromide.
Ta'amilosaga Fa'apitoa [α]20/D: Fa'ata'ita'i mago, C=8, vaifofo pa'u phosphate
Setete o Fofo (Transmittance): 0.5g i le 10ml o le H2O, spectrophotometer, 430nm, 10mm mafiafia sela.
Metala mamafa (Pb): 2.0g, (1), ref: 2.0ml o Pb Std.(0.01mg/ml)
Zinc (Zn): Metotia fa'atosina
Mea Fa'atatau: Metotia HPLC
Ma'imau ile Fa'agogo: I totonu o le masini, ile 70℃ mo le 4 itula
Toega i luga o le mumu (Sulfated): Su'ega AJI 13
Su'ega: Fa'ata'ita'iga mago, 200mg, 0.05mol/L I2 1ml=16.320mg C5H9NO3S
pH: 1.0g i le 100ml H2O
Fautuaina tapula'a ma tu'uga: Fa'asao atigi pusa i le vevela o le potu (1 tausaga).
N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) USP35 Metotia Su'ega
FAAMATALAGA
Acetylcysteine o loʻo i ai le NLT 98.0% ma le NMT 102.0% o le L-threonine (C5H9NO3S), faʻatatau i luga o le faʻamago.
FAATINOGA
A. FA'AULA'I INFRARED <197K>
SU'ESU'EGA
TULAGA
Vaega feavea'i: 6.8 g/L ole monobasic potassium phosphate.Fetuuna'i ile phosphoric acid ile pH ole 3.0.
Sodium metabisulfite solution: 0.5 mg/mL o le sodium metabisulfite i totonu o le vai, faatoa saunia.
Fofo masani ile totonu: 5 mg/mL ole USP L-Phenylalanine RS ile Sodium metabisulfite solution
Fofo fa'asoa masani: 10 mg/mL o le USP Acetylcysteine RS i le Sodium metabisulfite solution
Fofo masani: 0.5 mg/mL o le USP Acetylcysteine RS ma le 0.25 mg/mL o le USP L-Phenylalanine RS i le Sodium metabisulfite solution mai le Standard stock solution ma le Internal standard solution.
Fa'ata'ita'i fofo fa'asoa: 10 mg/mL o le Acetylcysteine i le Sodium metabisulfite solution.
Fa'ata'ita'iga vaifofo: 0.5 mg/mL o le Acetylcysteine ma le 0.25mg/mL o le USP L-Phenylalanine RS ile Sodium metabisulfite solution mai Fa'ata'ita'iga fa'asoa vaifofo ma totonu ole fofo masani.
Faiga fa'akomepiuta
(Va'ai Chromatography <621>, Faiga Fa'atonu.)
Auala: LC
Su'esu'e: UV 214 nm
Koluma: 3.9-mm × 30-cm;afifiina L1
Fuafuaga tafe: 1.5 mL/min
Tele tui: 5 µL
Faiga talafeagai
[FAAMANATU-O taimi faʻamautu mo le acetylcysteine ma le L-phenylalanine e tusa ma le 0.5 ma le 1.0, i le faasologa.]
Mana'oga talafeagai
I'uga: NLT 6 i le va o le acetylcysteine ma le L-phenylalanine
Feso'ota'iga tulaga ese: NMT 2.0%
Iloiloga
Faʻataʻitaʻiga: Fofo masani ma Faʻataʻitaʻiga fofo
Fa'atatau le pasene ole acetylcysteine (C5H9NO3S) ile vaega ole Acetylcysteine na ave:
I'uga = (RU/RS) × (CS/CU) × 100
RU = maualuga tali tali o le acetylcysteine i le L-phenylalanine mai le Sample solution
RS = maualuga tali fua faatatau o le acetylcysteine i le L-phenylalanine mai le fofo Standard
CS = fa'asalaina o le USP Acetylcysteine RS i le vaifofo masani (mg/mL)
CU = faʻamaualuga o le acetylcysteine i le faʻataʻitaʻiga fofo (mg / mL)
Tulaga talia: 98.0% -102.0% ile fa'amamago
LELEI
TOE FA'AVA'E I LE FA'AVAE <281>: NMT 0.5%
METAL MAMAFA, Metotia II <231>
[FA'ATOA-Fa'amalositino aua e ono tupu se pa.]
Su'esu'ega: Fa'asusu le fa'ata'ita'iga ile 2 mL ole nitric acid, ma fa'agasolo e pei ona fa'atonuina mo le tapenaga ole Su'ega.
Ta'iala talia: NMT 10 ppm
SU'E FA'AMANATU
FILI'IGA FA'AVAE, Ta'amilosaga Fa'apitoa <781S>
Puipui: Faafefiloi le 29.5 mL o le 1 N sodium hydroxide, 50 mL o le 1 M monobasic potassium phosphate, ma ia lava le vai e fai ai le 100 mL.Fetuuna'i i le pH o le 7.0 ± 0.1 e ala i le fa'aopoopoina o isi vaifofo, pe a mana'omia.
Fa'ata'ita'iga vaifofo: I totonu o se fagu volumetric 25-mL, fa'afefiloi le 1.25 g ma le 1 mL o le edetate disodium solution (1 i le 100), fa'aopoopo le 7.5mL o le sodium hydroxide solution (1 i le 25), ma fa'afefiloi e fa'amavae.Fa'asusu i le Buffer i le voluma.
Tulaga taliaina: +21° i le +27°
pH <791>: 2.0-2.8 i se vaifofo (1 i le 100)
MA'U'U I LE FAAMAGO <731>: Fa'amago se fa'ata'ita'iga i le mamafa e tusa ma le 50 mm o le mer cury i le 70° mo le 4 itula: e leiloa le NMT 1.0% o lona mamafa.
FAAOPOOPOGA
FAIGA MA TE'UINA: Fa'asa'o i totonu o koneteina fufusi, ma teu i le potu fa'atonutonu le vevela.
USP REFERENCE STANDARD <11>
USP Acetylcysteine RS
USP L-Phenylalanine RS
Fa'afefea ona Fa'atau?Fa'amolemole fa'afeso'ota'iDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Galuega & Fa'aoga ole N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) paʻu
1. N-Acetyl-L-Cysteine, e taʻua foi o le N-Acetylcysteine poʻo le Acetylcysteine (NAC), o se vailaʻau faʻamaʻi ma meaʻai faʻapitoa e faʻaaogaina muamua e avea o se sui mucolytic ma i le puleaina o le paracetamol (acetaminophen) overdose.O isi fa'aoga e aofia ai le fa'atumuina o le sulfate i tulaga, e pei o le autism, lea e ono fa'aumatia ai le cysteine ma le sulfur amino acids.
2. O le N-Acetyl-L-Cysteine o se mea e maua mai i le cysteine lea e faʻapipiʻi ai se vaega acetyl i le atom nitrogen.O lo'o fa'atauina lenei fa'aputuga e fai ma fa'aopoopoga mea'ai e masani ona ta'ua ai a'afiaga e puipuia ai le ate.E fa'aaogaina e fai ma vaila'au tale aua e motusia ai fusi o le disulfide i le mucus ma fa'afefeteina, e faigofie ai ona tale.O le gaioiga foi lea o le motusia o fusi o le disulfide lea e aoga ai i le fa'amama o le mucus mafiafia e le masani ai i tagata gasegase o le cystic ma le pulmonary fibrosis.
3. Acetylcysteine o se sui mucolytic ma malosi mucolytic aafiaga.O le vaega sulfhydryl o loʻo i totonu o le mole e mafai ona motusia le fusi o le disulfide i le glycoprotein polypeptide filifili i totonu o le sputum, ma faʻaitiitia ai le viscosity o le sputum, ma faʻafefe ai le sputum ma faigofie ona tale.O lenei oloa e mafai foi ona talepeina alava DNA i le purulent sputum, o lea e le gata ina faʻamaʻapeina le paʻepaʻe pipii paʻepaʻe, ae faʻapea foʻi le purulent sputum.Mo tagata mama'i o latou fa'amasani lautele e le aoga, o lenei oloa e mafai lava ona aoga.
4. E fa'aaogaina e fai ma vaila'au e fa'amavae ai le phlegm.E fa'aaogaina i su'esu'ega fa'aola kemikolo ma vaila'au e fai ma vaifofo mo le phlegm ma le acetaminophen poisoning.Biochemical reagent, vailaʻau, o lenei oloa e faʻaaogaina e pei o le expectorant, fai mai e faigofie ona faʻamama le phlegm.
5. O a'afiaga masani e aofia ai le faafaufau ma le pua'i pe a inu ile gutu. E ono mumu ma magese le pa'u i so'o se itu.E mafai fo'i ona tupu se ituaiga o anaphylaxis e le puipuia.E foliga mai e saogalemu ile maitaga.Mo le paracetamol overdose, e galue e ala i le faʻateleina o le maualuga o le glutathione, o se antioxidant e mafai ona faʻaumatia mea oona malepelepe o paracetamol.A manava, e galue o se mucolytic e ala i le faʻaitiitia o le mafiafia o le mucus.
6. Acetylcysteine na muamua pateni i le 1960 ma amata ona faʻaaogaina i le falemaʻi i le 1968. O loʻo i luga o le World Health Organization's List of Essential Medicines, o loʻo lisiina ai vailaʻau sili ona saogalemu ma sili ona aoga e manaʻomia i se faiga faʻalesoifua maloloina.E maua o se vaila'au lautele ma e taugofie.
7. O le N-Acetyl-L-Cysteine o le acetylated form of L-cysteine lea e sili atu ona faʻaoga lelei ma faʻaaogaina.O se antioxidant foi e fesoasoani e tetee atu ai i siama.O le N-Acetyl-l-Cysteine ua faʻaaogaina e fai ma puipuiga o le ate ma talepe ai le pulmonary ma bronchial mucus.
8. E mafai e le N-Acetyl-L-Cysteine ona faʻateleina le maualuga o le glutathione i sela.
9. O le N-Acetyl-L-Cysteine o se amino acid e mana'omia, o se tasi o na o le tolu amino acids o lo'o i ai le sulfur, o isi o le taurine (lea e mafai ona gaosia mai le L-cysteine) ma le L-methionine lea e mafai ai e le L-cysteine. e gaosia i totonu o le tino e ala i le tele o laasaga.
10. O le N-Acetyl-L-Cysteine e mafai ona galue o se antioxidant, e mafai ona puipuia faʻamaʻi ate, ma e mafai ona fesoasoani e faʻamalo le lautele o lauulu o loʻo iai pe a fai e le aunoa.
11. Fa'aoga i fa'alapotopotoga fa'afoma'i I le avea ai ma sui o le manava, e mafai ona fa'aaogaina e fai ma vaila'au mo le fa'amama phlegm drums.e mafai ona togafitia le bronchitis.le gata i lea, e mafai ona faaaoga N-Acetyl-L-Cysteine e fai ma vaifofo pe a oona acetaminophen.
12. Fa'aoga i fanua fa'alelei N-Acetyl-L-Cysteine e i ai se aafiaga tele i le fa'amamaina o fa'ama'i fua o le okesene ma isi oxides ma fa'agesegese ai le faagasologa o le matua, e mafai fo'i ona fa'alavelaveina le gaosiga o le melanin, ma e fesoasoani e fa'aumatia le freckle i luga o le pa'u.
13. Fa'aoga ile fafaga manu N-Acetyl-L-Cysteine e mafai ona fa'aogaina e fai ma fafaga fa'aopoopo.
14. O mea teuteu e masani ona faʻaaogaina mo vai matagofie, vai paʻu, kulimi tausiga paʻu o le la.E iai lana galuega e puipuia ai le soifua matua.N-Acetyl-l-Cysteine e mafai ona puipuia lelei ma togafitia manu'a fa'avevela.E mafai e le N-acetyl Cysteine ona aveese le paʻu o le melanin lava ia, suia le natura o le paʻu lava ia, o le paʻu e avea ma paʻepaʻe masani.
15. Mea'ai faaopoopo.Faʻaaogaina i falaoa, e faʻaleleia ai le faʻavaeina o le gluten ma faʻaleleia le faʻafefeteina, faʻafefe, puipuia le matua.Fa'aoga i sua masani e puipuia ai le vaitamini C mai le fa'ama'iina ma puipuia ai le sua mai le liu enaena.