Octreotide Acetate CAS 83150-76-9 Peptide Purity (HPLC) ≥98.0% API Tulaga Maualuga
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua o Octreotide Acetate (CAS: 83150-76-9) faʻatasi ai ma le maualuga.Ruifu Chemical o lo'o tu'uina atu se fa'asologa o peptide GMP.E mafai e Ruifu ona tuʻuina atu i le lalolagi atoa, tau faʻatauvaʻa, laʻititi ma tele tele avanoa.Fa'atau Octreotide Acetate,Please contact: alvin@ruifuchem.com
Igoa Vailaau | Octreotide Acetate |
Synonyms | SMS 201-995;Samilstin;Octreotide-LAR; |
Fa'asologa | D-Phe-c[Cys-Phe-D-Trp-Lys-Thr-Cys]-Thr-ol |
ATAATA | [FCFWKTCT(Disulfide Bridge: Cys2-Cys7)] |
Numera CAS | 83150-76-9 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o I Kilograms |
Fuafua mole | C49H66N10O10S2 |
Molecular Weight | 1019.24 |
Lisi Lisi | >140℃(Tes.) |
Malosi | 1.39±0.10g/cm3 |
Solubility | Solu i le Acetic Acid, DMSO, ma Methanol |
Maumau | Hygroscopic |
Temp. | Nofoaga malulu & mago (2~8 ℃).Pu'aisa |
Pepa | COA, MS, HPLC, NMR, MSDS, ma isi. |
Vaega | GMP Peptides |
WGK Siamani | 3 |
Tulaga Manaomia | Ato Aisa, Ato Desiccant |
Fa'ailoga | Ruifu Chemical |
Aitema | Tulaga Fa'atonu | I'uga |
Fa'aaliga | Pa'u Pa'epa'e | Pa'u Pa'epa'e |
Solubility | Solu i le Suavai po'o le 1% Acetic Acid i se fa'atonuga o le ≥1mg/ml e maua ai se fofo manino e leai ni lanu. | Fa'atatau |
Su'esu'ega Amino Acid (Saunia e HPLC) | Thr: 0.7 ~ 1.1 | 0.9 |
Cys: 1.0 ~ 2.2 | 1.9 | |
Lys: 0.9 ~ 1.3 | 1.1 | |
Phe: 1.8~ 2.2 | 1.9 | |
THR-OL: 0.6~1.3 | 0.9 | |
Trp: 0.4~1.1 | 0.8 | |
Peptide Purity (Saunia e HPLC) | ≥98.0% (e ala i le Vaega Fa'atasi) | 99.81% |
Mea Fa'atatau (Saunia e HPLC) | Aofa'i Fa'aleaga (%) ≤2.0% | 0.19% |
Le sili ona le mama nofofua (%) ≤1.0% | 0.12% | |
Acetate Content (HPLC) | 5.0~12.8% | 9.6% |
Suavai (Karl Fischer) | ≤7.0% | 2.7% |
TFA Content (Karl Fischer) | ≤0.25% | 0.13% |
Fa'asinomaga Fa'ailo | -45.0°~-55.0° (C=0.5, 95% HAc) | -51.5° |
Su'ega | 95.0~105.0% (Anhydrous, Acetic Acid Free) | 99.0% |
Mafua'aga o Oloa | Fa'asusu | |
Fa'alogo | Na'o Su'esu'ega, ae le mo le Fa'aaogaina e Tagata | |
Fa'ai'uga | Ua fa'ata'ita'iina le oloa ma fa'amalieina fa'amatalaga | |
Fa'aoga | GMP Peptides;Mea Fa'afoma'i Gaoioiga (API) |
afifi:Vial palasitika (fa'apitoa mo le fa'apipi'iina o le peptide) po'o le vial tioata, aofa'i e tusa ai ma manaoga o tagata fa'atau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i le malulu ma mago (2 ~ 8 ℃) faleteuoloa mai mea e le fetaui.Puipui mai le malamalama ma le susu.
Va'a:Tu'u atu i le lalolagi atoa e FedEx / DHL Express.Tuuina atu vave ma faatuatuaina tiliva.
O le Octreotide Acetate (Sandostatin) o se peptide analog o le hormone somatostatin, o se faʻataʻitaʻiga somatostatin umi e faʻaalia mo le puleaina o faʻamaʻi i le acromegaly ma le gastroenteropancreatic tuma.O isi fa'aoga talafeagai o lo'o su'esu'eina e aofia ai le ma'i suka, psoriasis ma le fa'ama'i o le Alzheimer.O le Octreotide Acetate (Sandostatin) o se peptide synthetic analogue o le hormone somatostatin.O ana gaioiga e aofia ai le taofia o le pituitary secretion o le tuputupu aʻe hormone ma le faʻalavelaveina o le pancreatic islet cell secretion o le inisalini ma le glucagon.E le pei o le somatostatin, o loʻo i ai le plasma afa-ola o ni nai minute, o le Octreotide o loʻo i ai le plasma elimination afa-ola o le 1 i le 2 itula.O le alu ese o le vailaʻau e masani lava ile fatu.O le Octreotide e faʻaitiitia ai le gaogao o le manava ma faʻalavelaveina le faʻamaʻi o le gallbladder.
Peptide vailaʻau Novartis Sandostatin (Octreotide Acetate), o se somatostatin octapeptide derivatives faanatura synthetic, e taofia ai se aafiaga pharmacological tutusa ma le somatostatin, ma o le aafiaga e umi.O faʻamatalaga mo Octreotide Acetate e aofia ai le acromegaly;Faʻaitiitia o faʻamaoniga ma faʻailoga e fesoʻotaʻi ma le gastroenteropancreatic endocrine neoplasia;Ma le aoga i le Carcinoid Tumors o loʻo maua i le carcinoid syndrome, tumo VIP, ma le glucagon tuma.E le gata i lea, o le Octreotide Acetate mo gastrinomas / Zollinger-Ellison syndrome (e masani ona tuʻufaʻatasia ma inhibitors pamu proton poʻo H2 receptor blockers), Insulinomas (puipuiga muamua o le hypoglycemia ma le tausia o le suka toto masani), o le fua faatatau lelei o le tuputupu aʻe o le hormone faʻamalolo mea tumo e. e tusa ma le 50%.
O le Octreotide Acetate o se vailaʻau faʻalesoifua maloloina a le Vasega B, o se vailaʻau faʻapitoa o le octapeptide o le somatostatin, pe a faʻatusatusa i le somatostatin masani, o le afa-ola o le somatostatin e manino lava le faʻaumiumi ma o loʻo i ai aʻafiaga faʻafomaʻi tutusa, e aofia ai le faʻasaina o le gaioiga o le tuputupu aʻe o le hormone, faʻasaina. ole gastric acid, pancreatic enzyme, glucagon ma le inisalini fa'alilo, ma le fa'aitiitia o le tafe toto visceral, fa'aitiitia le gaogao gastrointestinal.Pe a faʻatusatusa i le somatostatin, o le octreotide e umi lona afa-ola, e sili atu le filifilia mo le faʻalavelaveina o le faʻaogaina o le hormone tuputupu aʻe nai lo le taofiofia o le faʻaogaina o le inisalini, ma e le mafua ai le toe faʻaleleia o le hypersecretion o le hormone.1, Pulea le taotoga poʻo le faʻamaʻiina o le radiation e le mafai ona lelei le pulea o le faʻamaʻi i tagata mamaʻi e iai faʻamaoniga o le acromegaly ma faʻaitiitia ai le hormone tuputupu aʻe (GH) insulin-pei o le tuputupu aʻe -1 (1GF-1) maualuga plasma.E mafai fo'i ona fa'aoga le Sandostatin e togafitia ai tagata mama'i e maua i le acromegaly e le'o mafai pe le naunau e faia se taotoga, po'o le togafitia o tagata mama'i e maua i le acromegaly e le'i faia le togafitiga fa'avevela.2. Fa'aitiitia o fa'a'ailoga e feso'ota'i ma tuma o le endocrine gastroenteropancreatic (GEP) e pei ole tuma o le carcinoid ma fa'aaliga o le ma'i o le carcinoid.Sandostatin e le o se vailaʻau faʻamaʻi kanesa ma e le faʻamaloloina ai nei gasegase.3, Puipuia o faʻalavelave pe a uma le taotoga pancreatic.4, Liver cirrhosis maʻi ma gastric-esophageal variceal toto e mafua mai i togafitiga faʻafuaseʻi, hemostasis ma le puipuia o le toe toto, Sandostatin e tatau ona tuʻufaʻatasia ma endoscopic sclerotherapy ma isi togafitiga faʻapitoa.
O a'afiaga o lenei oloa o le Abdominal Pain, distension abdominal, Diarrhea, steatorrhea;Fausia ma'a ga'o;O le fa'apalepale o le kulukose e mafai ona fa'aitiitia pe fa'ateteleina i le amataga o togafitiga, ona mafai lea ona fa'aleleia;Talosaga umi e aunoa ma le gaosiga o le antibody endogenous, e leai se toe faʻaalia poʻo se faʻalavelave leaga pe a taofi le vailaʻau pe faʻaitiitia vave.2~8 deg C mo le teuina umi.