Olopatadine Hydrochloride Intermediate CAS 27710-82-3 Mama>99.0% (HPLC)
Fa'atau ta'imua ole Olopatadine Hydrochloride Intermediates
Olopatadine Hydrochloride CAS 140462-76-6
Isoxepac CAS 55453-87-7
[3-(Dimethylamino)propyl]triphenylphosphonium Bromide Hydrobromide CAS 27710-82-3
Please Contact: alvin@ruifuchem.com
| Igoa Vailaau | [3-(Dimethylamino)propyl]triphenylphosphonium Bromide Hydrobromide |
| Synonyms | (3-Dimethylaminopropyl)triphenylphosphonium Bromide HBr |
| Numera CAS | 27710-82-3 |
| CAT Numera | RF2698 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
| Fuafua mole | C23H28Br2NP |
| Molecular Weight | 509.27 |
| Lisi Lisi | 283.0~285.0 ℃ |
| Maumau | Hygroscopic |
| Solubility | Chloroform (La'iti), Methanol (La'iti) |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pa'epa'e i le Pa'u Pa'epa'e Pa'epa'e |
| Mama / Suʻesuʻega Metotia | >99.0% (HPLC) |
| Su'ega / Su'esu'ega Metotia | >99.0% (Titaration) |
| Ma'imau ile Fa'amago | <0.50% |
| Le mama nofofua | <0.50% |
| Aofa'i Fa'aleaga | <1.00% |
| 1 H NMR Alaleo | Osi ma le Fauga |
| Tulaga Su'ega | Pisinisi Tulaga |
| Fa'aoga | Vaeluaga ole Olopatadine Hydrochloride (CAS: 140462-76-6) |
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[3-(Dimethylamino)propyl]triphenylphosphonium Bromide Hydrobromide (CAS: 27710-82-3) o se vaeluaga ole Olopatadine Hydrochloride (CAS: 140462-76-6).Olopatadine Hydrochloride ose vaila'au fa'ama'i.E i ai a'afiaga e lua o le taofiofia o le tu'uina atu o le histamine ma filifili fa'afete'ena'i le tali atu o le HI, ma e leai se fa'alavelave fa'alavelave fa'alotoifale ma a'afiaga o'ona o le loto e masani ai i vaila'au fa'afeagai fa'ama'i a le HI.Olopatadine Hydrochloride e le gata e mafai ona taofiofia le tuʻuina atu o le histamine mai sela mast, ae faʻapea foʻi ona faʻafeiloaʻi i le H1 receptors sili atu ona filifilia, ma e leai se aʻafiaga i α adrenergic receptors, dopamine receptors, ma M1 ma M2 receptors.Faatasi ai ma i latou, o aʻafiaga o le fatugalemu o le tino e toalaiti, o se augatupulaga fou o vailaʻau antiallergic o filifiliga.Olopatadine o se faʻalavelave malosi, filifilia o le H1 histamine receptor (Ki = 16-41.1 nM), faʻatasi ai ma le tele o fesoʻotaʻiga maualalo mo le H2 ma le H3 faʻafeiloaʻi (Ki = 43.4 ma le 172 μM, faasologa).E poloka ai le suiga o le phosphoinositide e mafua mai i le histamine i sela vavae ese (IC50 = 9.5-39.9 nM) ma puipuia ai anaphylaxis paʻu paʻu i isumu (ED50 = 49 μg / kg) ma anaphylactic bronchoconstriction i puaa guinea (ID50 = 30 μg / kg).Ole Olopatadine e aoga ile togafitia ole rhinitis ma le conjunctivitis.E taofia ai foi le mageso i tagata mama'i e pulea lelei le urticaria tumau.I totonu o tagata, o lenei antihistamine e le mafua ai le faʻaleagaina o le mafaufau poʻo le psychomotor i tui faʻapitoa.
