Omeprazole Sulfide CAS 73590-85-9 Mama>99.0% (HPLC) Falegaosimea
Ruifu Sapalai Vailaau Omeprazole Intermediates ma maualuga mama
Omeprazole CAS 73590-58-6
Omeprazole Hydroxy Compound CAS 86604-78-6
Omeprazole Chloride Compound CAS 86604-75-3
Omeprazole Sulfide CAS 73590-85-9
2-Mercapto-5-Methoxybenzimidazole CAS 37052-78-1
2-Cyano-3-Methylpyridine CAS 20970-75-6
2,3,5-Trimethylpyridine CAS 695-98-7
Igoa Vailaau | Omeprazole sulfide |
Synonyms | Ufiprazole;Omeprazole Sulfur Eteru;Esomeprazole EP Le mama C;Omeprazole EP Le mama C;5-Methoxy-2-[[(4-Methoxy-3,5-Dimethyl-2-Pyridyl)methyl]thio]benzimidazole;5-Methoxy-2-{[(4-Methoxy-3,5-Dimethyl-2-Pyridinyl)methyl]thio}-1H-Benzimidazole |
Numera CAS | 73590-85-9 |
CAT Numera | RF-PI1914 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C17H19N3O2S |
Molecular Weight | 329.42 |
Lisi Lisi | 122.0 i le 126.0 ℃ |
Solubility | Solu i le Methanol |
Malosi | 1.28±0.10g/cm3 |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e i le Pa'epa'e Pa'epa'e po'o tioata |
Mama / Suʻesuʻega Metotia | >99.0% (HPLC) |
Ma'imau ile Fa'amago | <1.00% |
Toega i luga o le mumu | <0.20% |
Metala mamafa (pei o le Pb) | <20ppm |
Le mama nofofua | <0.50% |
Aofa'i Fa'aleaga | <1.00% |
Alaleo Infrared | E tusa ai ma le Fauga |
Proton NMR Alaleo | E tusa ai ma le Fauga |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | Vaeluaga ole Omeprazole / Esomeprazole |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
Omeprazole Sulfide (CAS: 73590-85-9) o se vaeluaga o loʻo faʻaaogaina i le gaosiga o le gastric proton pump inhibitors, Omeprazole (CAS: 73590-58-6) ma le Esomeprazole (CAS: 119141-88-7), Esomeprazole Sodium ( CAS: 161796-78-7).I le avea ai o se oloa faʻaleagaina, o loʻo lipotia mai e avea o se faʻalavelave faʻapitoa o le cytochrome P450 2C19 i totonu o microsomes ate tagata (IC50 = 9.7 μM).Omeprazole Sulfide o se metabolite o le Omeprazole.Esomeprazole Sodium o le masima masima o le esomeprazole.O se vailaʻau faʻasaina e masani ona faʻaaogaina, lea na muamua faʻaleleia e le kamupani Suetena Astra Zeneca muamua.E a'afia i se fa'atosina pamu proton.O le iniseti pamu proton o le filifiliga muamua lea mo le togafitia o le ma'i ma'i peptic, gastro-oesophageal reflux faʻamaʻi ma isi faʻamaʻi e fesoʻotaʻi ma vai.I le taimi nei e masani ona faʻaaogaina ile falemaʻi PPI e aofia ai ituaiga e lima: Omeprazole, Lansoprazole, Rabeprazole, Pantoprazole ma Esomeprazole.I le avea ai ma PPI muamua, o le aoga o fualaau oona o le omeprazole i le togafitia o faʻamaʻi e fesoʻotaʻi ma le acid ua lauiloa lautele.O le Esomeprazole o le S-isomer o le Omeprazole, lea e mafai ona fa'aitiitia ai le fa'aliloina o le gatric acid e ala i masini fa'apitoa.O le iniseti faapitoa mo le iniseti pamu proton i le sela parietal.Ona o le lelei o le gasegase o le esomeprazole, e maualuga atu le bioavailability ma sili atu pharmacokinetics faifai pea nai lo lona sui, Omeprazole Sodium, faʻateleina le vailaʻau e oʻo atu i le pamu proton.O lana matafaioi o le pulea o le gastric acid e sili atu le lelei nai lo isi fa'atosina pamu pamu e pei o Lansoprazole, Pantoprazole, ma Rabeprazole.