Palbociclib CAS 571190-30-2 Mama >99.5% (HPLC) API Falegaosi
Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
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Igoa Vailaau | Palbociclib |
Synonyms | PD-0332991;Otava-Bb 1115529;Ibrance |
Numera CAS | 571190-30-2 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C24H29N7O2 |
Molecular Weight | 447.54 |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e po'o le Pa'epa'e Pa'epa'e |
1H NMR Alaleo | Osi ma le Fauga |
HPLC | Osi ma le Fauga |
Mea Fa'atatau | |
Le mama o le tagata lava ia | <0.50% |
Aofa'i Fa'aleaga | <1.00% |
Ma'imau ile Fa'amago | <0.50% |
Toega i luga o le mumu | <0.10% |
Metala mamafa | <10ppm |
Mama / Suʻesuʻega Metotia | >99.5% (HPLC) |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | API, I Togafitiga o le Kanesa o le Susu |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
Palbociclib (CAS: 571190-30-2) ose fa'agata o le cyclin-dependent kinase (CDK) e mafai ona tuʻu tautala ma gaioiga antineoplastic.Palbociclib filifili filifili cyclin-faalagolago kinase 4 (CDK4) ma le 6 (CDK6), ma taofia le retinoblastoma (Rb) protein phosphorylation i le amataga o le vaega G1 e tau atu i le puʻeina o le taamilosaga.Ole mea lea e taofia ai le toe faia o DNA ma fa'aitiitia ai le fa'atuputeleina ole tumo.Palbociclib o le sui muamua lea o le vasega fou o vailaʻau o le cyclin-dependent kinase inhibitors.Ole a'afiaga lea e fa'atapula'aina ai le fa'atuputeleina ole sela (tupu ma le vaevaega ole sela).E fa'aaogaina e fai ma sui o le antineoplastic i le kanesa o le susu maualuga pe metastatic.