Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1 Su'ega 97.5~102.0% Falegaosimea
Ruifu Sapalai Vailaau Fa'aMama Maualuga
Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1
N-Methyl Paroxetine CAS 110429-36-2
| Igoa Vailaau | Paroxetine Hydrochloride Hemihydrate |
| Synonyms | (3S,4R)-(-)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine Hydrochloride Hemihydrate;Paxil;Seroxat;BRL29060 Hydrochloride Hemihydrate;BRL29060A Hemihydrate;Paroxetine-D4 HCl |
| Numera CAS | 110429-35-1 |
| CAT Numera | RF-PI1946 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
| Fuafua mole | C19H20FNO3·HCl·1/2H2O |
| Molecular Weight | 374.84 |
| Lisi Lisi | 140.0~143.0 ℃ |
| Ta'amilosaga Fa'apitoa [α]20/D | -88.0° i le -92.0° (C=1, MeOH, Calcd.on anh.substance) |
| Solubility | E le mafai ona solu i le Vai;E matua solu i le Dimethylformamide, Methanol;Solu i le Ethanol |
| Fa'ailoga | Ruifu Chemical |
| Mataupu | Fa'amatalaga | I'uga |
| Fa'aaliga | Pa'epa'e po'o le Toeitiiti Pa'epa'e Pa'u tioata | Fa'atatau |
| Faailoaina A | E tatau ona o gatasi le fusi o le infrared absorption ma le spectrum fa'asino | Fa'atatau |
| Faailoaga B | O le vaega pito i luga ma le taimi e teu ai le su'ega fofo e tatau ona ogatasi ma le fofo fa'asino | Fa'atatau |
| Faailoaina C | Vai (e KF) | Fa'atatau |
| Faailoaga D | Tali a Chlorides | Fa'atatau |
| Le mama D | ≤0.20% | Toesea |
| Le mama G | ≤0.001% | |
| Mea Fa'atatau | Le mama A: ≤0.30% | 0.03% |
| Le fa'ailoaina o mea leaga: Mo ta'itasi le mama, ≤0.10% | 0.06% | |
| Aofa'i Fa'aleaga: ≤0.50% | 0.10% | |
| Metala mamafa | ≤0.002% | <0.002% |
| Vai (e KF) | 2.20%~2.70% | 2.46% |
| Lefulefu Sulfated | ≤0.10% | <0.10% |
| Su'ega | 97.5% ~ 102.0% (Mata'ita'i Anhydrous) | 100.2% |
| Solvents totoe | ||
| Methanol | ≤0.30% | 0.001% |
| Acetone | ≤0.50% | 0.001% |
| Isopropanol | ≤0.50% | 0.04% |
| Dichloromethane | ≤0.06% | Leai |
| Toluene | ≤0.089% | 0.003% |
| Fa'ai'uga: Fa'atatau ile EP7.0. | ||
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
Paroxetine Hydrochloride Hemihydrate (CAS: 110429-35-1) o se tasi o mea sili ona malosi ma filifilia o le serotonin reuptake inhibitors (SSRI);vailaau fa'ama'i.O se mea e maua mai i le phenylpiperidine, ose ST (serotonin transporter/5-HT) e sili ona malosi ma filifili le fa'aogaina o le inhibitor.E galue e ala i le fusifusia i le ST (serotonin transporter / SERT) faʻatasi ma le maualuga maualuga (Ki = 05 nM).Antidepressant ma le popole i vivo.Paroxetine hydrochloride e mafai ona faʻaaogaina e togafitia ai le atuatuvale, o se vailaʻau faʻamaʻi fou.E mafai foʻi ona faʻaaogaina e togafitia ai le faʻalavelave faʻafuaseʻi, faʻalavelave popole lautele, faʻalavelave popole faʻaagafesootai, faʻalavelave faʻalavelave faʻalavelave (OCD), le mautonu, faʻamaʻi muamua, faʻamaʻi vave ma isi faʻamaʻi, faʻatasi ai ma togafitiga lelei ma faʻaitiitia faʻalavelave leaga.Ia togafitia ituaiga uma o le atuatuvale.E aofia ai le fa'anoanoa fa'atasi ma le popolevale ma le fa'alavelave fa'alavelave.Fa'ailoga fa'anoanoa masani: vaivai, fa'aletonu le moe, leai se fiafia ma le fiafia i gaioiga i aso uma, leai se 'ai.A maeʻa ona faʻamalieina le aʻafiaga faʻamalolo, e mafai ona taofia le toe tupu mai o le atuatuvale.
