Pazopanib Hydrochloride CAS 635702-64-6 Mama>99.0% (HPLC) API Fa'aaliga Fa'aalia Ata

Pazopanib Hydrochloride CAS 635702-64-6 Mama >99.0% (HPLC) API Falegaosi

Fa'amatalaga Puupuu:

Igoa vaila'au: Pazopanib Hydrochloride

CAS: 635702-64-6

Fa'aaliga: Pa'epa'e ile Pa'u Samasama Laititi

Mama: >99.0% (HPLC)

Tyrosine kinase inhibitor inhibitor mo le togafitia o le gasegase o le tino mamaʻi poʻo le sarcoma tino vaivai

API Tulaga Maualuga, Gaosiga Fa'apisinisi

Inquiry: alvin@ruifuchem.com

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Fa'amatalaga Oloa

Oloa Fa'atatau

Faailoga o oloa

Fa'amatalaga:

Tuuina atu a le Faumea ma le Mamalu Maualuga ma le Tulaga Lelei
Igoa vaila'au: Pazopanib Hydrochloride
CAS: 635702-64-6
Tyrosine kinase inhibitor receptor mo le togafitiga o le kanesa o le tino o le tino poʻo le sarcoma o le tino vaivai ua maua muamua le chemotherapy.
API Tulaga Maualuga, Gaosiga Fa'apisinisi

Meatotino tau vailaau:

Igoa Vailaau	Pazopanib Hydrochloride
Synonyms	Pazopanib HCl;GW786034 HCl;Votrient;5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide Hydrochloride
Numera CAS	635702-64-6
CAT Numera	RF-API93
Tulaga Fa'asoa	I Fa'atauga, Oloa Fua e O'o i le selau Kilograms
Fuafua mole	C21H23N7O2S.ClH
Molecular Weight	473.987
Solubility	DMSO
Lisi Lisi	300.0~304.0 ℃
Fa'ailoga	Ruifu Chemical

Fa'amatalaga:

Aitema	Fa'amatalaga
Fa'aaliga	Pa'epa'e i'a Laititi Samasama Pa'u
Fa'ailoaga	Ole alaleo ole absorption infraed ole fa'ata'ita'iga fa'ata'ita'iga e fetaui lelei ma le tulaga masani
Toega i luga o le mumu	≤0.50%
So'o se Fa'aleaga Ta'ito'atasi	≤0.30%
Aofa'i Fa'aleaga	≤1.50%
Metala mamafa	≤10ppm
Mama / Suʻesuʻega Metotia	≥99.0% (HPLC)
Tulaga Su'ega	Pisinisi Tulaga
Fa'aoga	API, Tyrosine kinase fa'ainitaneti talitali

Paket & Teuina:

afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.

Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.

Tulaga lelei:

FAQ:

Talosaga:

Pazopanib Hydrochloride (CAS 635702-64-6) ole multi-tyrosine kinase inhibitor ole vascular endothelial growth factor receptor (VEGFR) -1, VEGFR-2, VEGFR-3, platelet-derived growth factor receptor (PDGFR) -α ma - β, fibroblast growth factor receptor (FGFR) -1 ma -3, cytokine receptor (Kit), interleukin-2 receptor-inducible T-cell kinase (Itk), lymphocyte-specific protein tyrosine kinase (Lck), ma le transmembrane glycoprotein receptor tyrosine kinase (cFms).In vitro, pazopanib faʻasaina le autophosphorylation o le VEGFR-2, Kit, ma le PDGFR-beta receptors.I vivo, pazopanib faʻalavelaveina le VEGF-induced VEGFR-2 phosphorylation i mama isumu, angiogenesis i se faʻataʻitaʻiga o le isumu, ma le tuputupu aʻe o nisi xenografts tumo tagata i isumu.Na fa'amaonia mo le kanesa o le fatu fatu e le US Food and Drug Administration i le 2009 ma o lo'o fa'atau atu i lalo o le igoa tau fefa'ataua'iga Votrient e le kamupani gaosi vaila'au, GlaxoSmithKline.Votrient ose kinase inhibitor ua fa'ailoaina mo le togafitia o tagata mama'i ua maua i: 1) fa'amasani toto toto maualuga.2) sarcoma o le tino vaivai ua maua muamua le chemotherapy.