Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9 Posaconazole Tulaga Maualuga Maualuga
Falegaosi oloa ma le mama maualuga ma le mautu lelei
Posaconazole Related Intermediates Commercial Production
Posaconazole CAS 171228-49-2
Posaconazole Intermediate POA CAS 149809-43-8
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
Diethyl L-(+)-Tartrate CAS 87-91-2
Igoa Vailaau | Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate |
Synonyms | Posaconazole Intermediate |
Numera CAS | 184177-81-9 |
CAT Numera | RF-PI290 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C23H23N3O3 |
Molecular Weight | 389.45 |
Malosi | 1.296 |
Tulaga Va'a | I lalo ole Temperature Ambient |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Enaena enaena i le Efuefu Pata |
Mama / Suʻesuʻega Metotia | ≥99.0% (HPLC) |
Ma'imau ile Fa'amago | ≤0.50% |
Toega i luga o le mumu | ≤0.20% |
Metala mamafa | ≤20ppm |
Le mama nofofua | ≤0.50% |
Aofa'i Fa'aleaga | ≤1.0% |
Tulaga Su'ega | Enterprise Standard |
Fa'aoga | Vaitaimi ole Posaconazole (CAS 171228-49-2) |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate (CAS 184177-81-9) o se Intermediate o Posaconazole (CAS 171228-49-2).Posaconazole o se lautele-alaala, lona lua o augatupulaga, triazole faʻatasi ma gaioiga faʻamaʻi.Na faʻamaonia mo le faʻaaogaina faafomaʻi i le Iunaite Setete ia Setema 2006, ma o loʻo avanoa o se vailaʻau lautele.Posaconazole o se vailaʻau faʻamaʻi triazole faʻatau atu i le Iunaite Setete e Schering-Plough i lalo o le igoa tau fefaʻatauaʻiga Noxafil.Posaconazole e galue e ala i le faʻalavelaveina o le faʻapipiʻiina vavalalata o filifili acyl o phospholipids, faʻaleagaina ai galuega a nisi faʻaogaina o le enzyme system e pei o le ATPase ma enzymes o le faʻaogaina o le eletise, ma faʻafefe ai le tuputupu aʻe o le gaʻo.E faia lenei mea e ala i le taofia o le tuʻufaʻatasiga o le ergosterol e ala i le taofia o le enzyme lanosterol 14a-demethylase ma le faʻaputuina o methylated sterol precursors.