Posaconazole Intermediate POA CAS 149809-43-8 Falegaosimea Maualuga Maualuga
Sapalai Falegaosi Posaconazole Fesoʻotaʻiga Vaavaʻa, Gaosiga Faʻapisinisi
Posaconazole CAS 171228-49-2
Posaconazole Intermediate POA CAS 149809-43-8
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
Diethyl L-(+)-Tartrate CAS 87-91-2
Igoa | Posaconazole Intermediate POA |
Synonyms | (5R-cis) -Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester;(3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate |
Numera CAS | 149809-43-8 |
CAT Numera | RF-PI291 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i le selau Kilograms |
Fuafua mole | C21H21F2N3O4S |
Molecular Weight | 449.47 |
Malosi | 1.40 |
Tulaga Va'a | La'uina i lalo ole vevela ole ambient |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e i le Efuefu Pa'epa'e Pa'epa'e |
Fa'ailoaga | IR E tusa ai ma tulaga masani |
Lisi Lisi | 100.0-102.0 ℃ |
Ta'amilosaga Fa'apitoa [a]20/D | -40.0° i le -48° (C=1, CHCl3) |
Ma'imau ile Fa'amago | ≤0.50% |
Toega i luga o le mumu | ≤0.20% |
Metala mamafa | ≤20ppm |
Mea Fa'atatau | |
Tele le mama | ≤0.40% |
POA-Enantiomer | ≤0.10% |
POA-Diastereomer | ≤0.20% |
Tagata Ta'ito'atasi Le Iloa Le mama | ≤0.20% |
Aofa'i Fa'aleaga | ≤1.0% |
Mama | ≥99.0% |
Su'ega | 98.0%~102.0% (mea fa'ama'i) |
Tulaga Su'ega | Enterprise Standard |
Fa'aoga | Vaitaimi ole Posaconazole (CAS 171228-49-2) |
afifi: Fagu, taga pepa alumini, pusa pepa, 25kg / Paʻu, poʻo le tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama, susu ma le afaina o meaola faalafua.
(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester (CAS 149809-43) -8) o le Intermediate o Posaconazole (CAS 171228-49-2).Posaconazole o se vailaʻau antifungal triazole e poloka ai le tuʻufaʻatasiga o le ergosterol e ala i le taofia o le enzyme lanosterol 14α-demethylase ma le faʻaputuina o methylated sterol precursors, sili atu le malosi i le faʻalavelaveina o le 14α-demethylase nai lo itraconazole.