Potassium Bis(trimethylsilyl)amide CAS 40949-94-8 (0.5M Fofo ile Toluene)
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Igoa Vailaau | Potassium Bis(trimethylsilyl)amide |
Synonyms | Hexamethyldisilazane Potassium Salt;Potassium Hexamethyldisilazane;KHMDS |
Numera CAS | 40949-94-8 |
CAT Numera | RF-PI2227 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C6H18KNSi2 |
Molecular Weight | 199.49 |
Fa'apuna | 111℃ |
Malosi | 0.877 g/mL ile 25℃ |
Vasega o Tulaga Lamatia | 3 (8);Suavai mu, pala |
Fa'aputuga Vaega | II |
Solubility | Faʻafefiloi ma Terahydrofuran, Eteru, Benzene ma Toluene |
Suavai Solubility | Tali ma Vai |
Maaleale Hydrolytic | 8: Tali vave ma le susu, vai, pProtic Solvents |
Maumau | Susū maaleale, Ea maaleale, vevela vevela.Teu I lalo ole Nitrogen.E mafai ona fai se maa.Ambient Temperature. |
Saogalemu | Mata'utia-E Mafai ona Fa'atatau le Totogi o La'u o Oloa Mata'utia Faaopoopo |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Samasama i le Enaena Suavai |
Isi Fa'aleaga | ≤3.00% |
Anotusi o Active Base | 0.45~0.55 M |
Tulaga Su'ega | Pisinisi Tulaga |
afifi:Fagu, pe tusa ai ma manaoga o tagata faatau.
Tulaga teuina:E maaleale i le susu ma le ea.Teu i se nofoaga malulu.Taofi mau ia tapuni le atigipusa i se nofoaga mago ma lelei le savili.O koneteina o lo'o tatala e tatau ona toe fa'amaufa'ailogaina ma fa'atumauina sa'o ina ia puipuia ai le tafe.Uu ma teu i lalo o le kesi lega.E le fetaui ma vailaʻau faʻamaʻi malosi.
Fa'amatalaga o Tulaga Lamatia:Suavai e mu tele ma le ausa.E mafua ai le mu tuga o le pa'u ma le faaleagaina o mata.E mafua ai le leaga tele o mata.Ua masalomia o le faaleagaina o le fausiaina po o le pepe e lei fanau mai.E ono afaina ai totoga e ala i le fa'aumiumi po'o le fa'aalia pea.E ono mafua ai le tulemoe po'o le niniva.
Potassium Bis(trimethylsilyl)amide (0.5M Solution in Toluene) (masani fa'apu'upu'u o le KHMDS) (CAS: 40949-94-8) o se fa'avae malosi, e le o ni nucleophilic fa'atasi ma le pKa o le 26 (fa'atusatusa i le lithium diisopropylamide, i le 36. ).O loʻo maua faʻapisinisi e pei o se malo ma o se fofo i le tele o solvents (ex. THF, 2Me-THF, toluene, ma le MTBE).O mea fa'apena tutusa e aofia ai le lithium bis(trimethylsilyl)amide (LiHMDS) ma le sodium bis(trimethylsilyl)amide (NaHMDS).Fa'avae malosi megasteric non-nucleophilic.O vailaʻau faʻapitoa, faʻaaogaina i le gaosiga o cephalosporins synthetic.KHMDSose vaila'au fa'aogaina e fa'aoga i le chromatography fa'aogaina maualuga.E faʻaaogaina e fausia ai faʻalavelave faʻamautu ma le potassium, ona vavae ese lea e le koluma.O lo'o fa'aogaina fo'i le KHMDS i su'esu'ega fa'aola kemikolo ma e fai ma fa'aputuga fa'aasymmetric synthesis.KHMDS o se faavae malosi o loʻo faʻaaogaina i le alkylation carbonyl compounds.KHMDS o loʻo faʻaaogaina i le sauniuniga o le 5-Azacytidine, o se vailaʻau antineoplastic.Faʻaaogaina foi i le sauniuniga o β3-AR agonists faʻaaogaina i faʻamaʻi faʻamalosi.E fa'aaogaina fo'i e fai ma mea fa'afofoga i le tapenaga o fa'alavelave fa'apipi'i lanthanide o lo'o fa'aaogaina i tali fa'avili filifilia.