PyAOP CAS 156311-83-0 Fa'amama >99.0% (HPLC) Falegaosi Mea Fa'apipi'i

(7-Azabenzotriazol-1-yloxy) tripyrrolidinophosphonium Hexafluorophosphate (PyAOP) (CAS: 156311-83-0) o loʻo faʻaaogaina e avea o se mea faʻapipiʻi faʻapipiʻi i le faʻasologa o le peptide faʻasolosolo.E sili atu nai lo le HATU, aua e le faʻafefe i le N-terminus o le peptide.Pe a fa'atusatusa i mea e maua mai i le HOBt, o le PyAOP (ma le HOAt i le lautele) e sili atu ona fa'aalia ona o le fa'aopoopoina o le nitrogen.
O le PyAOP o se masima phosphonium o loʻo faʻaaogaina e fai ma mea faʻapipiʻi faʻapipiʻi i le faʻapipiʻiina o le peptide solid-phase, e aunoa ma le faia o ni faʻalavelave faʻatasi ma le amino terminal.O le PyAOP ose fa'atupuina ole HOAt.
O le PyAOP o se masima phosphonium e maua mai le HOAt na faʻaaogaina ai se peptide reagent.O le PyAOP e mautu e pei o se vaifofo malosi ma i le DMF, e aoga i le faʻaogaina o le peptide faʻavae ma le faʻaogaina o vaifofo, faʻamanuiaina i vailaʻau amino faʻafefeteina, i le faʻavaeina o peptides cyclic ma i le faʻaogaina o le faʻaogaina o peptides faʻailoga fluorescently.E maua e le PyAOP ni fua sili ona lelei ile fua ole tali lelei ma taofia ai le tuuga.O le PyAOP o le pyrrolidino analogue o le AOP ma sa mamanuina ma le faʻamoemoe o le faʻatupuina o se oloa e le oona nai lo le HMPA, lea e gaosia ma le AOP.
Reagent mo le tuufaatasia o: Cyclic RGC pentapeptides mo functionalization e ala i kiliki kemisi;su'esu'ega o le kulukose felumulu'i;ReactIR™ tafe sela
Reagent mo: Disulfide bond engineering;Heteroaryl eter synthesis;Fa'amalieina o le fa'atulafonoina fa'agata i luga ole phosphorylated cyclic peptide antagonists ole Grb2-SH2 domain.