Pyridine-3-Sulfonyl Chloride CAS 16133-25-8 Mama ≥98.5% (GC) Vonoprazan Fumarat Intermediate Factory
Tuuina atu le Vonoprazan Fumarate ma le Intermediate Intermediate
5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
Igoa Vailaau | Pyridine-3-Sulfonyl Chloride |
Synonyms | 3-Pyridinesulfonyl Chloride;3-Pyridylsulfonyl Chloride;m-Pyridinesulfonyl Chloride;Piperidine-3-Sulfonylchloride |
Numera CAS | 16133-25-8 |
CAT Numera | RF-PI540 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C5H4ClNO2S |
Molecular Weight | 177.61 |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Suavai e leai se lanu po'o samasama samasama |
Mama / Suʻesuʻega Metotia | ≥98.5% (GC) |
Fa'apuna | 110.0~112.0℃/2mm Hg |
Le mama nofofua | ≤0.50% |
Aofa'i Fa'aleaga | ≤1.5% |
Tulaga Su'ega | Enterprise Standard |
Fa'aoga | Intermediate of Vonoprazan Fumarate (CAS: 1260141-27-2) |
afifi: Fagu, 25kg / paelo, poʻo e tusa ai ma manaʻoga o tagata faʻatau.
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu.
Pyridine-3-Sulfonyl Chloride (CAS: 16133-25-8) o se vaeluaga ole Vonoprazan Fumarate (CAS: 1260141-27-2).Vonoprazan Fumarate, na maua ma atiina ae e Takeda ma Otsuka, na faʻamaonia e le PMDA o Iapani ia Tesema 2014, ma ua faʻaalia mo togafitiga o le gastric ulcer, duodenal ulcer ma reflux esophagitis.O le Vonoprazan fumarate o loʻo i ai se faiga fou o gaioiga e taʻua o le potassium-competitive acid blockers, lea e faʻatauvaʻa faʻalavelave ai le fusifusia o ion potassium i le H +, K + -ATPase (faʻapitoa foi o le pamu proton) i le laasaga mulimuli o le faʻamalo o le gatric acid i totonu o sela parietal gastric.E le taofia e Vonoprazan le gaioiga o le Na +, K + -ATPase e oʻo lava i faʻatonuga 500 taimi maualuga atu nai lo latou IC50 faʻatatau ile gastric H +, K + -ATPase gaioiga.E le gata i lea, o le vailaʻau e le afaina i le gastric secretory state, e le pei o PPI.