(R)-(-)-3-Quinuclidinol CAS 25333-42-0 Mama ≥99.0% Chiral Mama ≥99.0%
| Igoa Vailaau | (R)-(-)-3-Quinuclidinol |
| Synonyms | (R)-3-Quinuklinol |
| Numera CAS | 25333-42-0 |
| CAT Numera | RF-CC117 |
| Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
| Fuafua mole | C7H13NO |
| Molecular Weight | 127.18 |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pa'epa'e po'o le Pa'epa'e Pa'epa'e |
| Fa'ailoa RT (e GC) | Fa'atasi ma le Fa'asinomaga Fa'asinomaga |
| Lisi Lisi | 212.0~224.0 ℃ |
| Ta'amilosaga Fa'apitoa [α]D20 | -40.0°~ -48.0° |
| Susū (KF) | ≤0.50% |
| Toega i luga o le mumu | ≤0.50% |
| Mama | ≥99.0% |
| Aofa'i Fa'aleaga | ≤1.00% |
| Chiral Mama | ≥99.0% |
| Enantiomer | ≤1.00% |
| Su'ega | 98.0%～101.0% (i luga ole Anhydrous Base) |
| Tulaga Su'ega | Pisinisi Tulaga |
| Fa'aoga | Chiral Compounds;Vailaau Fa'atekonolosi |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
Shanghai Ruifu Chemical Co., Ltd. o le taʻutaʻua taʻutaʻua ma le tuʻuina atu o (R)-(-)-3-Quinuclidinol (CAS: 25333-42-0) faʻatasi ai ma le maualuga, faʻaaogaina lautele i le faʻaogaina o meaola, faʻasologa o vailaʻau vavalo ma Active Pharmaceutical Ingredient (API) synthesis.(R)-(-)-3-Quinuclidinol e mafai ona faʻaaogaina e avea o se vaeluagalemu i le faʻasologa o le API (CAS: 242478-38-2).(CAS: 242478-38-2) o se vailaʻau antimuscarinic lea e faʻaaogaina e togafitia ai le manava oona e mafua ai faʻamaoniga o taimi, faanatinati, poʻo le le taofiofia.(CAS: 242478-38-2) o le M3 muscarinic receptor antagonist lea na atiaʻe ma faʻalauiloa mo le togafitiga o le vevela oona (pollakiuria) i Europa.M3 receptors ua a'afia i neurally evoked musele lamolemole contractions o le tami, ma M2 receptors ua masalomia foi o le faia o se matafaioi ona o lo latou pule i le musele detrusor.O le tuʻufaʻatasiga o le solifenacin e aofia ai le saunia o le racemic 1-Phenyl-1,2,3,4-Tetrahydroisoquinoline e ala i le cyclization o le N-(2-Phenylethyl) benzamide, ma le tali mulimuli ane i le ethyl chloroformate ma le transesterification ma (R) -3-Quinuclidinol .Chiral chromatography e maua ai le fa'aesea o le diastereomer mana'omia.I le isi itu, 1-Phenyl-1,2,3,4-Tetrahydroisoquinoline e mafai ona tuʻuina atu i le faʻaogaina o le (+) -Tartaric Acid aʻo leʻi togafitia ma le ethyl chloroformate ma le transesterification mulimuli ane.
