Rabeprazole Sodium CAS 117976-90-6 Mama>99.5% (HPLC) API Falegaosi
Ruifu Sapalai Vailaau Matautia Rabeprazole Sodium Intermediates
Rabeprazole Sodium CAS 117976-90-6
Rabeprazole Hydroxy Compound CAS 675198-19-3
Rabeprazole Chloride Compound CAS 153259-31-5
Igoa Vailaau | Rabeprazole Sodium |
Synonyms | 2-([4-(3-Methoxypropoxy)-3-Methylpyridin-2-yl]methylsulfinyl)-1H-Benzo[d]imidazole;Pariprazole |
Numera CAS | 117976-90-6 |
Tulaga Fa'asoa | I Fa'atauga, Oloa Fua e O'o i Tone |
Fuafua mole | C18H20N3NaO3S |
Molecular Weight | 381.42 |
Lisi Lisi | 140.0~141.0 ℃ |
Fa'ailoga | Ruifu Chemical |
Aitema | Fa'amatalaga |
Fa'aaliga | Pa'epa'e i'e Laititi lanu samasama samasama po'o le pauta;Hygroscopic |
Alaleo Infrared | E tusa ma le Fauga |
Proton NMR Alaleo | E tusa ma le Fauga |
ICP | Fa'amaonia le Sodium Component |
Solubility | Solu atoatoa i le Vai;E matua solu i le Ethanol, Chloroform;Solu i le Methanol |
pH | 9.5~12.0 |
Ma'imau ile Fa'amago | <1.00% |
Metala mamafa | <20ppm |
Mea Fa'atatau | (HPLC) |
Le mama A | <0.80% |
Le Fa'aleaga Mea | <0.20% |
Aofa'i Fa'aleaga | <1.00% |
Solvents totoe | (GC) |
Methylene Chloride | <600ppm |
Ethanol | <5000ppm |
Isopropyl Eteru | <5000ppm |
Acetone | <5000ppm |
Tapulaa Microbial | |
Faitauga Aerobe | ≤1000CFU/g |
E faitaulia le limu ma le fefete | ≤100CFU/g |
E. Coli | E toesea mo le kalama |
Mama / Suʻesuʻega Metotia | >99.5% (HPLC, Fa'amamago) |
Tulaga Su'ega | Pisinisi Tulaga |
Fa'aoga | API mo Anti-Ulcer |
afifi: Fagu, ato pepa alumini, 25kg/Kati Pusa, pe tusa ai ma manaoga o tagata faatau
Tulaga teuina:Teu i totonu o pusa faʻamaufaʻailoga i se nofoaga malulu ma mago;Puipui mai le malamalama ma le susu
Rabeprazole Sodium (CAS: 117976-90-6) ose fa'atosina pamu e fa'agata ai le gaosiga o le gatric acid i totonu o le manava.E tele lona fa'aoga fa'afoma'i: o le fa'atonutonuina o tulaga e a'afia ai le tele o le gaosiga o le gatric acid (eg Zollinger-Ellison syndrome), tulaga e fa'ateteleina e le gastric acid (fa'ata'ita'iga o le papala o le gastrointestinal tract), ma tulaga e a'afia ai le fa'aumiumi o le fa'apa'iaina o le gastric acid (eg. faʻamaʻi faʻamaʻi gastroesophageal reflux).Rabeprazole e aoga foi faʻatasi ma vailaʻau faʻamaʻi mo le togafitia o le pathogen Helicobacter pylori, lea e faʻaleleia atili i siosiomaga oona.O le mea lea, o le Rabeprazole Sodium ua faʻamaonia e le FDA mo le togafitiga o le GERD faʻaalia i tupulaga talavou ma tagata matutua, faʻamaloloina o le maʻi o le duodenal i tagata matutua, faʻaumatiaina o le Helicobacter pylori, ma tulaga o le hypersecretory pathologic.O le Rabeprazole Sodium e taofiofia le gaosiga o le gaʻo i totonu o le manava e ala i le taofiofia o le gastric H + / K + ATPase (hydrogen-potassium adenosine triphosphatase) i luga o le mea lilo o le gatric parietal cell.