Ramelteon Intermediate CAS 196597-78-1 Mama>98.5% (HPLC)
Ta'ita'i Gaosi ma Fa'atau oloa, Intermediates a Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-tasi CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
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| Igoa Vailaau | 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-tasi |
| Synonyms | 6,7-Dihydro-1H-Indeno[5,4-b]furan-8(2H)-tasi;Ramelteon Intermediate 1;Ramelteon I |
| le mama | Ramelteon le mama A |
| Numera CAS | 196597-78-1 |
| CAT Numera | RF2883 |
| Tulaga Fa'asoa | I Fa'atauga, Gaosi Gaosi 20 Tone i le Masina |
| Fuafua mole | C11H10O2 |
| Molecular Weight | 174.20 |
| Lisi Lisi | 133.0 i le 137.0 ℃ |
| Fa'apuna | 334.2±42.0℃ |
| Malosi | 1.288±0.06 g/cm3 |
| Vasega o Tulaga Lamatia | Fa'aitaita |
| Fa'ailoga | Ruifu Chemical |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pa'epa'e i'e samasama samasama pauta pa'epa'e |
| Mama / Suʻesuʻega Metotia | >98.5% (HPLC) |
| Lisi Lisi | 133.0 i le 137.0 ℃ |
| Vai (saunia e Karl Fischer) | <0.50% |
| Toega i luga o le mumu | <0.10% |
| Aofa'i Fa'aleaga | <1.50% |
| 1 H NMR Alaleo | Osi ma le Fauga |
| Tulaga Su'ega | Pisinisi Tulaga |
| Fa'aoga | Intermediate of Ramelteon (CAS: 196597-26-9) |
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1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one (CAS: 196597-78-1) o loʻo faʻaaogaina e avea o se vaeluaga o Ramelteon (CAS: 196597-26-9) , o le fatu o le tina o le synthesizing Ramelteon.O Ramelteon o le muamua lea i se vasega fou o sui moe e filifili faʻatasi i le MT1 ma le MT2 faʻafeiloaʻi i le suprachiasmatic nucleus (SCN), nai lo le fusifusia i le GABA receptors.E le faʻaalia e Ramelteon soʻo se faʻamaufaʻailoga taua i GABAA faʻafeiloaʻi, lea e fesoʻotaʻi ma faʻalavelave popole, myorelaxant, ma aʻafiaga amnesic.Ramelteon e mafai ona faʻaaogaina mo le le mautonu, aemaise lava le tuai o le moe.O Ramelteon e leʻi faʻaalia e maua ai le faʻalagolago ma e leʻi faʻaalia le faʻaleagaina, ma o le faʻamavaeina ma le toe faʻafoʻiina o le le mautonu lea e masani ai GABA modulators e le o iai i le ramelteon.O nisi o foma'i latou te fa'aogaina le ramelteon mo le togafitia o le ma'i o le vaega o le moe tuai.Togafitiga o le le moe (faigata le moe).E mafai fo'i ona fa'aoga mo isi tulaga e pei ona fuafuaina e lau foma'i.Ramelteon o se agonist melatonin.E galue e ala i le galue i le melatonin receptors i le faiʻai, lea e fesoasoani ia te oe e te moe ai.
